Results 101 to 110 of about 1,270,897 (309)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Novel Biopesticides Based on Recombinant Avidin for Protection of Crops Against Insect Pests [PDF]

, 2012
Farmers are required to increase their food productivity to meet the demand from a continually enlarging population. A major constraint on meeting this requirement is the damage created by insect pests.
HINCHLIFFE, GARETH
core  

Gel-Based Purification and Biochemical Study of Laccase Isozymes from Ganoderma sp. and Its Role in Enhanced Cotton Callogenesis

Frontiers in Microbiology, 2017
Basidiomycetous fungi, Ganoderma lucidum MDU-7 and Ganoderma sp. kk-02 secreted multiple laccase isozymes under diverse growth condition. Aromatic compounds and metal salts were also found to regulate the differential expression of laccase isozymes from ...
Krishna K. Sharma, Amit Kumar, Amit Kumar, Deepti Singh, Sakshi Arora, Amarjeet K. Singh, Sarvajeet S. Gill, Barkha Singhal   +7 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Haemoglobin mass and running time trial performance after recombinant human erythropoietin administration in trained men [PDF]

, 2013
<p>Recombinant human erythropoietin (rHuEpo) increases haemoglobin mass (Hbmass) and maximal oxygen uptake (v˙ O2 max).</p> <p>Purpose: This study defined the time course of changes in Hbmass, v˙ O2 max as well as running time trial ...
Wondimu, D.H., Chatterji Tushar, McClure, J.D., Padmanabhan Neal, Daskalaki Evangelia, Anderson Martin, Patel Rajan K., Wondimu, Diresibachew H., Jérôme Durussel, Anderson, Martin, Tushar Chatterji, John D McClure, Patel, Rajan K., Pitsiladis, Yannis P., Pitsiladis, Yannis; id_orcid, Chatterji, Tushar, Martin Anderson, Rajan K Patel, Evangelia Daskalaki, Yannis P Pitsiladis, Pitsiladis Yannis P., Neal Padmanabhan, McClure John D., Padmanabhan, Neal, Anderson, M., Pitsiladis, Y.P., Daskalaki, Evangelia, Durussel, Jérôme, Daskalaki, E., Chatterji, T., Padmanabhan, N., Durussel, J., Diresibachew H Wondimu, McClure, John D., Patel, R.K., Durussel Jérôme, Wondimu Diresibachew H.   +36 more
core   +2 more sources

RECOMBINATION AND INTRINSICALITY [PDF]

Ratio, 2008
AbstractIn this paper I argue that warrant for Lewis’ principle of recombination presupposes warrant for a combinatorial analysis of intrinsicality, which in turn presupposes warrant for the principle of recombination. This, I claim, leads to a vicious circularity: warrant for neither doctrine can get off the ground.
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Recombinant-IL-22 treatment prolongs the survival of Mtb-infected T2DM mice.

, 2019
One month after the induction of diabetes, T2DM mice were infected with ~100 CFU of aerosolized Mtb. Five months after Mtb infection, the mice were treated intravenously with recombinant IL-22 (100 ng/kg body weight, twice weekly) or PBS. (A) A schematic
Rajesh Kumar Radhakrishnan (5587778), Buka Samten (3404951), Ramya Sivangala Thandi (8098553), Venkata Sanjeev Kumar Neela (5587784), Ramakrishna Vankayalapati (306095), Madeline Kay McAllister (8098556), Deepak Tripathi (690264), Padmaja Paidipally (690262), Kamakshi Prudhula Devalraju (6009380), Vijaya Lakshmi Valluri (7422743)   +9 more
core   +1 more source

Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope [PDF]

, 1991
The regulatory immediate-early (IE) protein pp89 of murine cytomegalovirus induces CD8+ T lymphocytes that protect against lethal murine cytomegalovirus infection.
Ulrich, H. Koszinowski, Koszinowski, Ulrich H., Messerle, Martin, Matthias J. Reddehase, Hansjurgen Volkmer, Reddehase, Matthias J., Del Val, Margarita, Margarita Del Val, Martin Messerle, Volkmer, Hansjürgen, Hans-jurgen Schlicht, Schlicht, Hans-Jürgen   +12 more
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source