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Recombinators, recombinases and recombination genes of yeasts
Current Genetics, 1994Genetic recombination in the nuclear, organellar, and plasmid genomes of eukaryotic organisms occurs during mitosis and meiosis. Mitotic recombination is an important mechanism for the repair of DNA damaged by ultraviolet light, ionizing radiation, and chemical agents (Friedberg et al. 1991).
M S, Esposito +2 more
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Recombination in yeast and the recombinant DNA technology
Genome, 1989The development of methods to isolate eukaryotic genes, alter these genes in vitro and reintroduce them into the cell has had a major impact on the study of recombination in the yeast Saccharomyces cerevisiae. In this paper we discuss how recombinant DNA techniques have been employed in the study of recombination in yeast and the results that have ...
T D, Petes +9 more
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Breast Cancer Research and Treatment, 1996
Pseudomonas exotoxin has been genetically modified so that it targets cancer cells. This was accomplished by deleting its cell binding domain and replacing it with Fv fragments of antibodies that react with breast, colon, and other cancers. Several recombinant immunotoxins are now in clinical trials.
I, Pastan +3 more
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Pseudomonas exotoxin has been genetically modified so that it targets cancer cells. This was accomplished by deleting its cell binding domain and replacing it with Fv fragments of antibodies that react with breast, colon, and other cancers. Several recombinant immunotoxins are now in clinical trials.
I, Pastan +3 more
openaire +2 more sources
Current Protocols in Molecular Biology, 2006
AbstractThe study of protein en masse, or functional proteomics, depends on the availability of full‐length cDNAs in appropriate expression‐ready plasmid vectors for protein expression and functional analysis. Recombinational cloning is a universal cloning technique based on site‐specific recombination that is independent of the insert DNA sequence to ...
Jaehong, Park, Joshua, Labaer
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AbstractThe study of protein en masse, or functional proteomics, depends on the availability of full‐length cDNAs in appropriate expression‐ready plasmid vectors for protein expression and functional analysis. Recombinational cloning is a universal cloning technique based on site‐specific recombination that is independent of the insert DNA sequence to ...
Jaehong, Park, Joshua, Labaer
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Recombination: Meiotic Recombination in Fungi
1997New combinations of genetic material are generated by the molecular process of genetic recombination. Recombination can affect all types of DNA: nuclear (mitosis and meiosis), organellar and plasmid DNA. Mitotic recombination is rare compared to meiotic recombination and appears to involve a less complex process (Esposito et al.
Heike Röhr, Ulf Stahl, Ursula Kües
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2013
Homologous recombination is a complex process that has several important roles: repair of broken DNA, repair of disintegrated replication forks and generation of genetic diversity. Two independent recombination pathways, RecBCD and RecF(OR), operate in Escherichia coli. Both pathways are involved in the initial stages of recombination i.e.
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Homologous recombination is a complex process that has several important roles: repair of broken DNA, repair of disintegrated replication forks and generation of genetic diversity. Two independent recombination pathways, RecBCD and RecF(OR), operate in Escherichia coli. Both pathways are involved in the initial stages of recombination i.e.
openaire +2 more sources