Results 271 to 280 of about 282,766 (336)

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

Advanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song, Xiangxu Wang, Luqing Ha, Lamei Hu, Shuyuan Mei, Yue Liang, Yujie Zhao, Xingyin Yang, Qingyu Zhang, Yuanzhang Zhou, Jianhua Ding, Yan Liu, Qigang Zhou, Feng Han, Gang Hu, Ming Lu   +15 more
wiley   +1 more source

Mapping <i>C. difficile</i> TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling. [PDF]

mBio
Ward JS, Schreiber KJ, Tam J, Youn J-Y, Melnyk RA.   +4 more
europepmc   +1 more source

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

Papain expression in the <i>Escherichia coli</i> cytoplasm by T7-promoter engineering and co-expression with human protein disulfide isomerase (PDI) and thiol peroxidase (GPx7) genes. [PDF]

Appl Environ Microbiol
Hoque MA, Gross RA, Koffas MAG.
europepmc   +1 more source

Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein. [PDF]

Viruses
Bai S, Cui Y, Liao Q, Yi H, Liao Z, Zhang G, Wu F, Lu H.   +7 more
europepmc   +1 more source

Targeting Herpes Simplex Virus Glycoprotein D with Bispecific Antibodies: Expanding Therapeutic Horizons by Searching for Synergy. [PDF]

Viruses
Atanasiu D, Saw WT, Friedman HM, Cohen GH.   +3 more
europepmc   +1 more source

Prohibitin 1 tethers lipid membranes and regulates OPA1-mediated membrane fusion. [PDF]

J Biol Chem
Ban T, Kuroda K, Nishigori M, Yamashita K, Ohta K, Koshiba T.   +5 more
europepmc   +1 more source

Recombinant production of spider silk protein in Physcomitrella photobioreactors. [PDF]

Plant Cell Rep
Ramezaniaghdam M, Bohlender LL, Parsons J, Hoernstein SNW, Decker EL, Reski R.   +5 more
europepmc   +1 more source

Nanobody fusion enhances production of difficult-to-produce secretory proteins. [PDF]

J Biol Chem
Yan R, Zhang Y, Zhang H, Ma J.
europepmc   +1 more source

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Recombinant avidin and avidin–fusion proteins

Biomolecular Engineering, 1999
Both chicken egg-white avidin and its bacterial relative streptavidin are well known for their extraordinary high affinity with biotin (Kd approximately 10(-15) M). They are widely used as tools in a number of affinity-based separations, in diagnostic assays and in a variety of other applications. These methods have collectively become known as (strept)
Markku S. Kulomaa, Kari J. Airenne, Varpu Marjomäki   +2 more
openaire   +3 more sources