Results 61 to 70 of about 399,275 (342)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Design and Production of Arginine Deiminase-Azurin Recombinant Fusion Protein from Pseudomonas aeruginosa and its Confirmation by Western Blot

Novelty in Biomedicine, 2020
Background: Pseudomonas aeruginosa is a common Gram-negative, rod-shaped bacterium that has a unique genome that allowed the bacteria to produce various enzymes and proteins.
Mina Hadi, Mona Ghazi, Parvaneh Saffarian, Bahareh Hajikhani   +3 more
doaj   +1 more source

ACCUMULATION OF RECOMBINANT FUSION PROTEIN – SECRETORY ANALOG OF Ag85B AND ESAT6 MYCOBACTERIUM TUBERCULOSIS PROTEINS – IN TRANSGENIC Lemna minor L. PLANTS [PDF]

Biotechnologia Acta, 2015
Determination of the presence of the recombinant fusion protein (ESAT6-Ag85B(ΔTMD)-6His) and its accumulation level in duckweed plants (Lemna minor L.) was the aim of the research.
A.A.Peterson, M. Yu. Vasylenko, N. A. Matvieieva, M. V. Kuchuk   +3 more
doaj   +1 more source

A mini-review of TAT-MyoD fused proteins: state of the art and problems to solve. [PDF]

, 2018
open6siopenPatruno, M; Melotti L.; Gomiero, C; Sacchetto, R; Topel, O; Martinello, T.Patruno, M; Melotti, Luca; Gomiero, C; Sacchetto, R; Topel, O; Martinello ...

core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

DEVELOPMENT OF FUSION RECOMBINANT PROTEINS BASED ON VP6 AND VP8 OF HUMAN ROTAVIRUS A

Инфекция и иммунитет, 2014
Rotaviruses are the most frequent cause of children enteritis. This infection often leads to severe dehydration of organism. Many infectious diseases are accompanied by fluid loss being the most common cause of death.
I. V. Dukhovlinov, E. G. Bogomolova, E. A. Fedorova, A. S. Simbirtsev   +3 more
doaj   +1 more source

Native chick laminin-4 containing the beta 2 chain (s-laminin) promotes motor axon growth. [PDF]

, 1996
After denervation of muscle, motor axons reinnervate original synaptic sites. A recombinant fragment of the synapse specific laminin beta 2 chain (s-laminin) was reported to inhibit motor axon growth.
Brandenberger, R, Chiquet, M, Engel, J, Kammerer, RA   +3 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Efficient expression of fusion human epidermal growth factor in tobacco chloroplasts

BMC Biotechnology, 2023
Background Chloroplast transformation is a robust technology for the expression of recombinant proteins. Various types of pharmaceutical proteins including growth factors have been reported in chloroplasts via chloroplast transformation approach at high ...
Yunpeng Wang, Jieying Fan, Zhengyi Wei, Shaochen Xing   +3 more
doaj   +1 more source

Obtaining of the recombinant Rhil7-Cbd fusion protein

Faktori eksperimental'noi evolucii organizmiv, 2020
Aim. The purpose was to obtain the recombinant fusion protein based on the human interleukin-7 (rhIL7) and cellulose binding domain (CBD). Methods. The DNA sequences encoding rhIL-7 and CBD were subcloned into the pET24a(+). Vector containing the 6His-tag sequence for further chromatographic purification of the target protein. The cells of E.
M. O. Usenko, O. B. Gorbatiuk, O. V. Okunev, D. M. Irodov, M. V. Koval’chuk, V. A. Kordium   +5 more
openaire   +2 more sources