Results 61 to 70 of about 577,747 (248)
The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper
Despite the long history of use and the knowledge of the genetics and biochemistry of E. coli, problems are still possible in obtaining a soluble form of recombinant proteins in this system. Although, soluble protein can be obtained both in the cytoplasm
Svetlana V. Belenkaya+15 more
doaj +1 more source
FimH-based display of functional eukaryotic proteins on bacteria surfaces
The demand for recombinant proteins for analytic and therapeutic purposes is increasing; however, most currently used bacterial production systems accumulate the recombinant proteins in the intracellular space, which requires denaturating procedures for ...
Markus Chmielewski+5 more
doaj +1 more source
The exotoxins of certain strains of Staphylococcus aureus strains are able both to stimulate potent proliferation and induce anergy in T lymphocytes expressing the appropriate T cell Ag receptor V beta gene elements.
R. Buelow+5 more
semanticscholar +1 more source
gp43 is the major diagnostic antigen of Paracoccidioides brasiliensis, the agent of paracoccidioidomycosis (PCM) in humans. In the present study, cDNA of the gp43 gene (PbGP43) was obtained by reverse transcriptase PCR, inserted into a pGEX vector in ...
S. Diniz+5 more
semanticscholar +1 more source
To produce rarely secreted recombinant proteins in the yeast Saccharomyces cerevisiae, we developed a novel genome-wide optimal translational fusion partner (TFP) screening system that involves recruitment of an optimal secretion signal and fusion ...
Jung-Hoon Bae+7 more
semanticscholar +1 more source
Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase–RNase H domain exhibits polymerase and RNase H activities [PDF]
M.L. Wilhelm+2 more
openalex +2 more sources
Turn TRAIL Into Better Anticancer Therapeutic Through TRAIL Fusion Proteins
Background TNF‐related apoptosis‐inducing ligand (TRAIL) belongs to the tumor necrosis factor superfamily. TRAIL selectively induces apoptosis in tumor cells while sparing normal cells, which makes it an attractive candidate for cancer therapy ...
Yan Wang+7 more
doaj +1 more source
CD36 is a multifunctional cell-surface receptor that binds adhesion molecules such as thrombospondin-1 and collagen and modified lipids and/or lipoproteins.
Frieda A. Pearce+5 more
semanticscholar +1 more source
Contribution of defined amino acid residues to the immunogenicity of recombinantEscherichia coliheat-stable enterotoxin fusion proteins [PDF]
Isabelle Batisson, Maurice Der Vartanian
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Background Despite evidence suggesting a role in plant defence, the use of plant lectins in crop protection has been hindered by their low and species-specific insecticidal activity.
Fitches Elaine+2 more
doaj +1 more source