Results 21 to 30 of about 15,000 (182)

Wound Healing and ndash; A Proteomic Analysis of the Effect of Erythropoietin on Granulation Tissue Isolated from ePTFE Implants

Archives of Clinical and Experimental Surgery, 2014
Background: Erythropoietin is a multifunctional cytokine, with recent studies indicating a positive effect on wound healing in models of incisional and burn wounds.
Bekka Christensen, Vibeke Koudahl, Bent Honor and eacute;, Jens Overgaard, Tine Engberg Damsgaard, Henrik Vorum   +5 more
doaj   +1 more source

HUMAN RECOMBINANT ERYTHROPOIETIN GRADIENT DOSAGE INFLUENCE ON ISCHEMIC AND REPERFUSION LIVER INJURY [PDF]

Research Results in Pharmacology, 2015
We investigate influence of human recombinant erythropoietin different dosage on blood flow velocity and morphological changes in liver during ischemic and reperfusion injury. It was proved what optimal preconditioning dosage is 50 IU/kg.
Sergey Alehin, Dmytry Kolmykov, Mikhail Pokrovskii   +2 more
doaj   +3 more sources

Resistance of dialyzed patients to erythropoietin

Revista Brasileira de Hematologia e Hemoterapia, 2015
Resistance to recombinant human erythropoietin is a common condition in dialyzed patients with chronic kidney disease and is associated with more hospitalizations, increased mortality and frequent blood transfusions.
Michelle Teodoro Alves, Sandra Simone Vilaça, Maria das Graças Carvalho, Ana Paula Fernandes, Luci Maria Sant'Ana Dusse, Karina Braga Gomes   +5 more
doaj   +1 more source

Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects. [PDF]

PLoS ONE, 2012
BackgroundErythropoietin receptors have been identified in human skeletal muscle tissue, but downstream signal transduction has not been investigated.
Britt Christensen, Carsten Lundby, Niels Jessen, Thomas S Nielsen, Poul F Vestergaard, Niels Møller, Henriette Pilegaard, Steen B Pedersen, John J Kopchick, Jens Otto L Jørgensen   +9 more
doaj   +1 more source

Effects of recombinant human erythropoietin in normal humans

The Journal of Physiology, 2011
This review describes some of the physiological effects of recombinant human erythropoietin (EPO) in healthy humans. At the blood level EPO increases the arterial O2 content not only by increasing red blood cell volume, but also by an equally important decrease in plasma volume.
Lundby, Carsten, Olsen, Niels Vidiendal
openaire   +5 more sources

Neuroprotective mechanisms of erythropoietin in a rat stroke model

Translational Neuroscience, 2020
This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).
Juenemann Martin, Braun Tobias, Schleicher Nadine, Yeniguen Mesut, Schramm Patrick, Gerriets Tibo, Ritschel Nouha, Bachmann Georg, Obert Martin, Schoenburg Markus, Kaps Manfred, Tschernatsch Marlene   +11 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

A Review of Pleiotropic Potential of Erythropoietin as an Adjunctive Therapy for COVID-19

Journal of Clinical and Basic Research, 2022
Coronavirus disease 2019 (COVID-19) is a severe acute respiratory disease with a high prevalence. According to the research and statistical data, in January 2021, there have been 92,262,621 confirmed cases of COVID-19 and more than two million deaths ...
Fatemeh EmamiPari, Soroush Kamali, Ghazaleh Nikzad, Narges Roosta Navi, Sanaz Soltani, Mohamad Reza Kalani   +5 more
doaj