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Introduction: Discovery of Growth Hormone and Synthesis of Recombinant Human Growth Hormone
2016The most famous likely growth hormone (GH)-deficient individual was Charles S. Stratton (born February 4, 1838), nicknamed General Tom Thumb by P.T. Barnum who discovered him at age of 10. He was born to parents of normal height who were first cousins. His birth weight was nine and a half pounds, and he grew steadily until age 18 months. Thereafter, he
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Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1994
This study was to evaluate the efficacy, safety and immunogenicity of recombinant human growth hormone (rhGH) in treatment of children with growth hormone deficiency (GHD).We selected 15 children with GHD for a 12-month clinical trial and separated them into three groups with each 5 patients receiving one of the 3 tested rhGH (Saizen by Serono, Aubonne,
K C, Shih +6 more
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This study was to evaluate the efficacy, safety and immunogenicity of recombinant human growth hormone (rhGH) in treatment of children with growth hormone deficiency (GHD).We selected 15 children with GHD for a 12-month clinical trial and separated them into three groups with each 5 patients receiving one of the 3 tested rhGH (Saizen by Serono, Aubonne,
K C, Shih +6 more
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Whither Recombinant Human Growth Hormone?
Annals of Internal Medicine, 1996Christos S. Mantzoros, Alan C. Moses
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[How safe is the recombinant human growth hormone?]
Revista medica del Instituto Mexicano del Seguro Social, 2018In this paper, several aspects related to the safety of the use of biosynthetic human growth hormone are reviewed. For example, its classification as a biosynthetic drug, the phases that need to be performed in Mexico to verify its safety (obtaining, purification, preclinical studies, clinical trials, and finally observational clinical studies), as ...
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[Use of recombinant Human Growth Hormone (rHGH)].
Revista medica del Instituto Mexicano del Seguro Social, 2018Recombinant human growth hormone, synthesized in E.coli or mammalian cells cultures, is since 1985, a useful therapeutic resource to increase growth velocity and final height. In this paper are discussed the four phases (aims, security and efficacy, utility and efficiency) indispensables to define the start of treatment, as well as the absolute ...
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Recombinant Human Growth Hormone Therapy in HIV-Associated Wasting and Visceral Adiposity
Expert Review of Anti-Infective Therapy, 2005Marshall Glesby, Michael Yin
exaly
Long-Term Safety of Recombinant Human Growth Hormone in Children.
Journal of Clinical Endocrinology and Metabolism, 2010B Lippe
exaly

