Results 141 to 150 of about 508,275 (214)

Effect of recombinant protein production and release on microalgal fitness and the impact of environmental conditions for localized therapeutic delivery. [PDF]

J Biol Eng
Carvajal F, Vargas-Torres V, Becerra D, González-Quezada N, Egaña JT.   +4 more
europepmc   +1 more source

Analysis of Variability of Functionals of Recombinant Protein Production Trajectories Based on Limited Data. [PDF]

Int J Mol Sci, 2022
Liao S, Macharoen K, McDonald KA, Nandi S, Paul D.   +4 more
europepmc   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Enhancing recombinant protein production through Cre-loxP mediated chromosomal rearrangement evolution in Kluyveromyces marxianus. [PDF]

Commun Biol
Ren H, Zou Q, Song K, Yu Y, Zhou J, Mo W, Lu H.   +6 more
europepmc   +1 more source

Efficient CRISPR/Cas9-Mediated BAX Gene Ablation in CHO Cells To Impair Apoptosis and Enhance Recombinant Protein Production. [PDF]

Iran J Biotechnol, 2023
Rahimi A, Karimipoor M, Mahdian R, Alipour A, Hosseini S, Mohammadi M, Kaghazian H, Abbasi A, Shahsavarani H, Shokrgozar MA.   +9 more
europepmc   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Advances in Subcellular Accumulation Design for Recombinant Protein Production in Tobacco. [PDF]

Biodes Res
Song SJ, Diao HP, Guo YF, Hwang I.
europepmc   +1 more source

The Influence of Different Culture Media on the Growth and Recombinant Protein Production of Iranian Lizard Leishmania Promastigote. [PDF]

Iran J Parasitol, 2022
Abdi Ghavidel A, Aghamiri S, Jajarmi V, Bandehpour M, Kazemi B.   +4 more
europepmc   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Dataset for suppressors of amyloid-β toxicity and their functions in recombinant protein production in yeast. [PDF]

Data Brief, 2022
Chen X, Li X, Ji B, Wang Y, Ishchuk OP, Vorontsov E, Petranovic D, Siewers V, Engqvist MKM.   +8 more
europepmc   +1 more source