Results 91 to 100 of about 2,327,860 (219)
This meta‐analysis included 10 randomized controlled trials involving 1,116 patients with acute ischemic stroke. Compared with thrombolysis plus standard care, adjunctive acupuncture was associated with reduced neurological deficits (NIHSS: MD = −2.90), improved daily living function (Barthel Index: MD = 12.07), and higher clinical response rates (RR =
Geng Li +9 more
wiley +1 more source
Thrombolytic agents are frequently employed in the treatment of thrombosis in combination with early surgical exploration and management. Recombinant tissue plasminogen activator is a second generation thrombolytic agent, which acts specifically at the ...
Uygur, Safak +3 more
core +1 more source
Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini +20 more
wiley +1 more source
Thrombolytic therapy for ischemic stroke
Systemic intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is a proven effective treatment in a certain category of patients with ischemic stroke during the first 4.5 hours after onset of this disease.
Natalia Vyacheslavovna Pizova
doaj +1 more source
Trial of Steroids in Retinal Assault: A Case Series
Blunt trauma to the eye can present with transient or permanent visual loss. Mere observation might lead to improvement of vision in cases of transient visual loss whereas those with photoreceptor and optic nerve damage, permanent loss of vision is ...
Sharanyaa Krishnamoorthy +3 more
doaj +1 more source
ABSTRACT Background Ulcerative colitis (UC) is a challenging inflammatory bowel disease characterized by chronic inflammation of the colon's mucosal layer. Despite advances in medical research, UC lacks definitive diagnostic tests and targeted treatments.
Shuai Wang, Hualiang Deng, Dajuan Sun
wiley +1 more source
Cerebral Embolism Associated with Left Atrial Myxoma That Was Treated with Thrombolytic Therapy
We present a case of cerebral embolism associated with a left atrial myxoma that was treated with intravenous thrombolytic therapy. A 79-year-old right-handed man with no history of neurological or psychiatric illnesses was referred to our hospital ...
Naoto Kohno +5 more
doaj +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Lipoprotein(a), Endothelial Dysfunction and Cardiovascular Disease
ABSTRACT Lipoprotein(a) (Lp(a)) is a particle similar to low‐density lipoprotein cholesterol and is associated with apolipoprotein (A). High Lp(a) levels are a genetic, independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Endothelial cells, which form the continuous lining of the cardiovascular system, are crucial for vascular ...
Xianghui Zhou +5 more
wiley +1 more source
Objective To assess the efficacy of intravenous recombinant tissue plasminogen activator administered after 3 h following onset of ischaemic stroke.
M. Fareed K. Suri +5 more
core +1 more source

