Results 81 to 90 of about 236,609 (162)

Treponema pallidum mRNA-LNP vaccine candidate encoding TP0954 induces strongly protective immunity in rabbits

Frontiers in Immunology
IntroductionSyphilis is a sexually or vertically transmitted disease caused by the infection of Treponema pallidum (T. pallidum). Syphilis prevalence has risen globally despite the availability of effective treatments.
Zhiyu Lu, Yizhou Lu, Di Liu, Fangzhi Du, Qingyun Wu, Guoyang Liao, Yanan Wu, Rui-Li Zhang, Jian Zhou, Qianqiu Wang   +9 more
doaj   +1 more source

Immunogenicity and protection of octavalent influenza vaccine candidates using adjuvanted proteins or mRNA-LNPs in naïve mice

npj Vaccines
Currently used influenza vaccines primarily induce antibody responses against hemagglutinin (HA). Neuraminidase (NA) has been proposed as a complementary antigen to improve and potentially expand the breadth of influenza vaccine protection.
João Paulo Portela Catani, Anouk Smet, Tine Ysenbaert, Laura Amelinck, Koen Sedeyn, Xavier Saelens, Thorsten U. Vogel   +6 more
doaj   +1 more source

Current status of recombinant duck enteritis virus vector vaccine research

Frontiers in Veterinary Science
Duck enteritis virus (DEV), the pathogen of duck viral enteritis, belongs to the α-herpesvirus subfamily. Like other herpesviruses, it has a large genome with multiple non-coding and non-essential regions for viral replication.
Wen-Feng Jia, An-Ping Wang, Zhi Wu, Xin-Nuo Lei, Yu-Ting Cheng, Shan-Yuan Zhu   +5 more
doaj   +1 more source

Study of the immunological efficacy and safety of a candidate vaccine against Lassa hemorrhagic fever

Медицинская иммунология
Lassa hemorrhagic fever is an acute human infectious disease with high mortality rate and pandemic potential. To date, there are no approved drugs for the specific treatment or prevention of Lassa hemorrhagic fever in the world. The aim of this study was
O. Popova, O. V. Zubkova, T. A. Ozharovskaia, D. I. Zrelkin, D. V. Voronina, P. P. Goldovskaya, V. Yu. Kan, I. V. Dolzhikova, A. V. Kovyrshina, D. M. Grousova, I. A. Ermolova, D. V. Shcheblyakov, D. Yu. Logunov, A. L. Gintsburg   +13 more
doaj   +1 more source

Co-formulation of the rF1V plague vaccine with depot-formulated cytokines enhances immunogenicity and efficacy to elicit protective responses against aerosol challenge in mice

Frontiers in Immunology
This study evaluated a depot-formulated cytokine-based adjuvant to improve the efficacy of the recombinant F1V (rF1V) plague vaccine and examined the protective response following aerosol challenge in a murine model. The results of this study showed that
Darrell R. Galloway, Jiahui Li, Nguyen X. Nguyen, Frank W. Falkenberg, Frank W. Falkenberg, Lisa Henning, Robert Krile, Ying-Liang Chou, James N. Herron, J. Scott Hale, E. Diane Williamson   +10 more
doaj   +1 more source

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S., Konthur, Z., Maslov, D., Simpson, L.   +3 more
core   +1 more source

Securing poultry production from the ever-present Eimeria challenge [PDF]

, 2013
Blake, D P, Tomley, F M
core   +2 more sources

Adjuvants : an essential component of neisseria vaccines [PDF]

, 2009
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R., Balbao, J., Cabrera, O., Cuello, M., del Campo, J., Ferro, Valerie A., Gonzales, E., Romeu, B., Zayas, C.   +8 more
core  

Prolonged Neurological and Musculoskeletal Symptoms Following Shingrix Vaccination

Reports
Background and Clinical Significance: The recombinant zoster vaccine (Shingrix) helps prevent shingles and its complications in adults 50 and older. While minor side effects are common, severe adverse reactions are thought to be rare, and long-term side ...
Sabrina Hollar, Amna Khalid, Benjamin D. Brooks, Michael Wons   +3 more
doaj   +1 more source

UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine. [PDF]

Sci Rep, 2023
Vrablikova A, Fojtikova M, Hezova R, Simeckova P, Brezani V, Strakova N, Fraiberk M, Kotoucek J, Masek J, Psikal I.   +9 more
europepmc   +1 more source