Results 1 to 10 of about 503,053 (218)

Recombination and Genetic Diversity

Trends in Computational and Applied Mathematics, 2012
In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinating individuals distributed spatially.
Thamara Carvalho Coutinho, Telles Timóteo Da Silva, Gustavo Leal Toledo   +2 more
doaj   +6 more sources

Recombination rate and selection strength in HIV intra-patient evolution [PDF]

PLoS Comput Biol, 2010, 6(1): e1000660, 2009
The evolutionary dynamics of HIV during the chronic phase of infection is driven by the host immune response and by selective pressures exerted through drug treatment. To understand and model the evolution of HIV quantitatively, the parameters governing genetic diversification and the strength of selection need to be known.
A Eyre-Walker, A Jung, AE Jetzt, AR Templeton, AS Perelson, B Asquith, C Charpentier, C Kuiken, C Neuhauser, Christophe Fraser, CL Althaus, CTT Edwards, D Shriner, D Shriner, DJ Wilson, DN Levy, E Jones, E Simon-Loriere, G McVean, GA Bazykin, HY Lee, IM Rouzine, IM Rouzine, J Archer, J Chen, J Hunter, J Zhuang, JH Gillespie, L Chen, M Kimura, N Barton, N Barton, R Nielsen, R Shankarappa, RA Kaslow, RA Neher, RC Edgar, RC Griffiths, Richard A. Neher, RR Hudson, S Duffy, SA Seibert, SL Liu, T Leitner, T Nora, T Oliphant, Thomas Leitner, WJ Ewens, Y Yamaguchi   +48 more
arxiv   +14 more sources

Genetic Recombination as a Chemical Reaction Network [PDF]

arXiv, 2015
The process of genetic recombination can be seen as a chemical reaction network with mass-action kinetics. We review the known results on existence, uniqueness, and global stability of an equilibrium in every compatibility class and for all rate constants, from both the population genetics and the reaction networks point of view.
Hofbauer, Josef, Müller, Stefan
arxiv   +3 more sources

Genetic analysis of genome-scale recombination rate evolution in house mice. [PDF]

PLoS Genetics, 2011
The rate of meiotic recombination varies markedly between species and among individuals. Classical genetic experiments demonstrated a heritable component to population variation in recombination rate, and specific sequence variants that contribute to ...
Beth L Dumont, Bret A Payseur
doaj   +7 more sources

The asexual genome of Drosophila [PDF]

arXiv, 2017
The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic segments. Selection under linkage can induce clonal interference, a specific mode of evolution by competition of ...
Lässig, Michael, Mustonen, Ville, Schiffels, Stephan   +2 more
arxiv   +3 more sources

Similarity in recombination rate estimates highly correlates with genetic differentiation in humans. [PDF]

PLoS ONE, 2011
Recombination varies greatly among species, as illustrated by the poor conservation of the recombination landscape between humans and chimpanzees. Thus, shorter evolutionary time frames are needed to understand the evolution of recombination.
Hafid Laayouni, Ludovica Montanucci, Martin Sikora, Marta Melé, Giovanni Marco Dall'Olio, Belén Lorente-Galdos, Kate M McGee, Jan Graffelman, Philip Awadalla, Elena Bosch, David Comas, Arcadi Navarro, Francesc Calafell, Ferran Casals, Jaume Bertranpetit   +14 more
doaj   +5 more sources

Optimal Recombination in Genetic Algorithms [PDF]

arXiv, 2013
This paper surveys results on complexity of the optimal recombination problem (ORP), which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions. We consider efficient reductions of the ORPs, allowing to establish polynomial solvability or NP-hardness of the ORPs, as ...
Eremeev, Anton V., Kovalenko, Julia V.
arxiv   +3 more sources

Genome-wide atlas of loci involved in chromosomal recombination in common wheat [PDF]

BMC Plant Biology
Chromosomal recombination is a pivotal biological mechanism for generating novel genetic diversity, essential for plant breeding and genetic research endeavors.
Yanchun Peng, Xinru Lyu, Dengan Xu, Zunjie Wang, Xianchun Xia, Yuanfeng Hao, Hongya Wu, Wujun Ma   +7 more
doaj   +2 more sources

Cocirculation and replacement of SARS-CoV-2 variants in crowded settings and marginalized populations along the US-Mexico border

Salud Pública de México, 2023
Objective. To interrogate the circulating SARS-CoV-2 lin­eages and recombinant variants in persons living in migrant shelters and persons who inject drugs (PWID). Materials and methods.
Antoine Chaillon, Ietza Bojorquez, Jaime Sepúlveda, Alicia Yolanda Harvey-Vera, M Gudelia Rangel, Britt Skaathun, Sanjay R Mehta, Caroline Ignacio, Magali Porrachia, Davey M Smith, Steffanie A Strathdee   +10 more
doaj   +1 more source

Banana bunchy top virus genetic diversity in Pakistan and association of diversity with recombination in its genomes.

PLoS ONE, 2022
Banana Bunchy top virus (BBTV) is a multipartite circular single strand DNA virus that belongs to genus Babuvirus and family Nanoviridae. It causes significant crop losses worldwide and also in Pakistan.
Sana Bashir, Syed Muhammad Saqlan Naqvi, Aish Muhammad, Iqbal Hussain, Kazim Ali, Muhammad Ramzan Khan, Sumaira Farrakh, Tayyaba Yasmin, Muhammad Zeeshan Hyder   +8 more
doaj   +2 more sources