Results 31 to 40 of about 546,503 (279)

The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]

open access: yes, 2015
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X   +6 more
core   +2 more sources

An Eco-Evolutionary approach of Adaptation and Recombination in a large population of varying size [PDF]

open access: yes, 2014
We identify the genetic signature of a selective sweep in a population described by a birth-and-death process with density dependent competition. We study the limit behaviour for large K, where K scales the population size.
Smadi, Charline
core   +4 more sources

Reduced meiotic recombination in rhesus macaques and the origin of the human recombination landscape.

open access: yesPLoS ONE, 2020
Characterizing meiotic recombination rates across the genomes of nonhuman primates is important for understanding the genetics of primate populations, performing genetic analyses of phenotypic variation and reconstructing the evolution of human ...
Cheng Xue   +7 more
doaj   +1 more source

Complete genome sequences of two feline Leukemia virus subgroup B isolates with novel recombination sites [PDF]

open access: yes, 2013
It is generally accepted that all primary isolates of feline leukemia virus (FeLV) contain a subgroup A virus (FeLV-A) that is essential for transmission.
Bae   +12 more
core   +1 more source

Genetic Recombination and Molecular Evolution [PDF]

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 2009
Reduced rates of genetic recombination are often associated with reduced genetic variability and levels of adaptation. Several different evolutionary processes, collectively known as Hill-Robertson (HR) effects, have been proposed as causes of these correlates of recombination.
Charlesworth, B.   +3 more
openaire   +3 more sources

The asexual genome of Drosophila

open access: yes, 2017
The rate of recombination affects the mode of molecular evolution. In high-recombining sequence, the targets of selection are individual genetic loci; under low recombination, selection collectively acts on large, genetically linked genomic segments ...
Lässig, Michael   +2 more
core   +1 more source

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

open access: yeseLife, 2018
Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate
Hannes Mutschler   +7 more
doaj   +1 more source

Identification and manipulation of the molecular determinants influencing poliovirus recombination.

open access: yesPLoS Pathogens, 2013
The control and prevention of communicable disease is directly impacted by the genetic mutability of the underlying etiological agents. In the case of RNA viruses, genetic recombination may impact public health by facilitating the generation of new viral
Charles Runckel   +3 more
doaj   +1 more source

Recombination confounds the early evolutionary history of human immunodeficiency virus type 1: Subtype G is a circulating recombinant form [PDF]

open access: yes, 2007
Human immunodeficiency virus type I (HIV-1) is classified in nine subtypes (A to D, F, G, H, J, and K), a number of subsubtypes, and several circulating recombinant forms (CRFs).
Abecasis, Ana B.   +8 more
core   +2 more sources

Homologous Recombination in Clostridioides difficile Mediates Diversification of Cell Surface Features and Transport Systems

open access: yesmSphere, 2020
Illness caused by the pathogen Clostridioides difficile is widespread and can range in severity from mild diarrhea to sepsis and death. Strains of C. difficile isolated from human infections exhibit great genetic diversity, leading to the hypothesis that
Hannah D. Steinberg, Evan S. Snitkin
doaj   +1 more source

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