Results 101 to 110 of about 8,966 (220)

RecX facilitates homologous recombination by modulating RecA activities.

open access: yesPLoS Genetics, 2012
The Bacillus subtilis recH342 strain, which decreases interspecies recombination without significantly affecting the frequency of transformation with homogamic DNA, carried a point mutation in the putative recX (yfhG) gene, and the mutation was renamed ...
Paula P Cárdenas   +7 more
doaj   +1 more source

Mismatch repair in recombination of bacteriophage T4

open access: yesBiomolecular Concepts, 2012
The review focuses on the mechanism of mismatch repair in bacteriophage T4. It was first observed in T4 as an extra recombination mechanism, which contributed to the general recombination only when particular rII mutations were used as genetic markers ...
Shcherbakov Victor P.
doaj   +1 more source

Structural basis for Rap1-Rif1-Rif2 assembly : insights into budding yeast telomere architecture and functions [PDF]

open access: yes, 2012
Telomeres form the ends of eukaryotic linear chromosomes and are composed of specialized nucleoprotein complexes. They have been the subject of intense investigation over several decades, as telomere dysfunction has been associated with genome ...
Tianlai, Shi
core   +1 more source

Rtt107 phosphorylation promotes localisation to DNA double-stranded breaks (DSBs) and recombinational repair between sister chromatids.

open access: yesPLoS ONE, 2011
Efficient repair of DNA double-stranded breaks (DSB) requires a coordinated response at the site of lesion. Nucleolytic resection commits repair towards homologous recombination, which preferentially occurs between sister chromatids.
Pranav Ullal   +3 more
doaj   +1 more source

Splitting, joining and cutting : mechanistic studies of enzymes that manipulate DNA

open access: yes, 2010
Electronic version does not contain associated previously published materialDNA is a reactive and dynamic molecule that is continually damaged by both exogenous and endogenous agents.
McRobbie, Anne-Marie M.
core  

DNA repair in bacteroides fragilis

open access: yes, 2008
Includes abstract.Includes bibliographical leaves (leaves 89-101).Bacteroides fragilis is a gut commensal in both humans and animals where it benefits the host through metabolizing indigestible compounds, stimulating the immune system and protecting ...
Steffens, Laura Sione
core  

Recombinational DNA repair is regulated by compartmentalization of DNA lesions at the nuclear pore complex

open access: yes, 2015
The nuclear pore complex (NPC) is emerging as a center for recruitment of a class of "difficult to repair" lesions such as double-strand breaks without a repair template and eroded telomeres in telomerase-deficient cells. In addition to such pathological
Vincent Géli   +3 more
core   +1 more source

Meiotic double-strand break repair DNA synthesis tracts in Arabidopsis thaliana.

open access: yesPLoS Genetics
We report here the successful labelling of meiotic prophase I DNA synthesis in the flowering plant, Arabidopsis thaliana. Incorporation of the thymidine analogue, EdU, enables visualisation of the footprints of recombinational repair of programmed ...
Miguel Hernández Sánchez-Rebato   +2 more
doaj   +1 more source

Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study

open access: yesBMC Cancer, 2006
Background Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of developing cancer.
Aase Steinar   +10 more
doaj   +1 more source

Transcription-coupled nucleotide excision repair and its regulation by the DNA damage checkpoint

open access: yes, 2009
Elaborate DNA repair mechanisms have evolved, allowing cells to repair damages in their genomes. Nucleotide excision repair (NER) removes a variety of helix-distorting lesions, including those caused by ultraviolet (UV) irradiation.
Taschner, M.J.
core  

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