Results 71 to 80 of about 8,966 (220)

ruvA Mutants that resolve Holliday junctions but do not reverse replication forks

, 2008
RuvAB and RuvABC complexes catalyze branch migration and resolution of Holliday junctions (HJs) respectively. In addition to their action in the last steps of homologous recombination, they process HJs made by replication fork reversal, a reaction which ...
Bradley Alison Sylvia, Tsaneva, I, Tsaneva Irina, Bénédicte Michel, Baharoglu Zeynep, Irina Tsaneva, Zeynep Baharoglu, Marie Le Masson, Michel, B, Bradley, AS, Baharoglu, Z, Le Masson Marie, Michel Bénédicte, Alison Sylvia Bradley, Le Masson, M   +14 more
core   +1 more source

Recombinant Amelogenin as a Potential Alternative to Enamel Matrix Derivatives in Periodontal Regeneration: A Scoping Review of Its Biological Activity, Synthesis and Delivery Systems

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objective The objective of this review is to evaluate the existing literature on the regenerative potential of recombinant amelogenin, with a particular emphasis on the biological activity, synthesis, and delivery systems relevant to periodontal regeneration.
Jie Dan Denny Luo, Jennifer Mardini, Raymond Lee, Fariba Dehghani, Aaron Schindeler   +4 more
wiley   +1 more source

Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase [PDF]

, 2009
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Duplication and transmission of chromosomes require precise control of chromosome replication and segregation.
Lloyd, RG, Robert G. Lloyd, Christian J. Rudolph, Amy L. Upton, Upton, AL   +4 more
core   +1 more source

NurA Is Endowed with Endo- and Exonuclease Activities that Are Modulated by HerA: New Insight into Their Role in DNA-End Processing. [PDF]

PLoS ONE, 2015
The nuclease NurA and the ATPase HerA are present in all known thermophilic archaea and cooperate with the highly conserved MRE11/RAD50 proteins to facilitate efficient DNA double-strand break end processing during homologous recombinational repair ...
Mariarosaria De Falco, Federico Catalano, Mosè Rossi, Maria Ciaramella, Mariarita De Felice   +4 more
doaj   +1 more source

The Mre11 protein interacts with both Rad50 and the HerA bipolar helicase and is recruited to DNA following gamma irradiation in the archaeon Sulfolobus acidocaldarius

, 2008
Background: The ubiquitous Rad50 and Mre11 proteins play a key role in many processes involved in the maintenance of genome integrity in Bacteria and Eucarya, but their function in the Archaea is presently unknown.
Patrick Forterre, Elie, Christiane, White, Malcolm F, White, Malcolm, Christiane Elie, Constantinesco, Florence, Quaiser, Achim, Forterre, Patrick, Achim Quaiser, Florence Constantinesco, Malcolm F White   +10 more
core   +1 more source

Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier [PDF]

, 2011
Most DNA double-strand breaks (DSBs) in S- and G2-phase cells are repaired accurately by Rad51-dependent sister chromatid recombination. However, a minority give rise to gross chromosome rearrangements (GCRs), which can result in disease/death.
Ledesma, Jennifer, Whitby, Matthew C., Castagnetti, S, Sofueva, Sevil, Alexander Lorenz, Steinacher, R, Fekret Osman, Lorenz, Alexander, Sofueva, S, Ledesma, J, Castagnetti, Stefania, Whitby, Matthew, Steinacher, Roland, Sevil Sofueva, Stefania Castagnetti, Osman, F, Lorenz, A, Matthew C. Whitby, Whitby, MC, Osman, Fekret, Roland Steinacher, Jennifer Ledesma   +21 more
core   +1 more source

DNA Polymerase e - More Than a Polymerase

The Scientific World Journal, 2003
This paper presents a comprehensive review of the structure and function of DNA polymerase e. Together with DNA polymerases a and d, this enzyme replicates the nuclear DNA in the eukaryotic cell.
Helmut Pospiech, Juhani E. Syväoja
doaj   +1 more source

Cold comfort for change: Stream mats as biological indicators of ecosystem processes in the McMurdo Dry Valleys, Antarctica

Journal of Phycology, Volume 62, Issue 2, Page 261-292, April 2026.
Abstract Glacier‐fed streams (GFSs) make ideal systems for studying climate‐related changes. Some of the best‐studied GFSs are found in the McMurdo Dry Valleys (MDVs) of Antarctica, one of the Earth's coldest and driest deserts. Despite their harsh and isolated nature, MDV GFSs represent an oasis of life in a landscape visually devoid of it, with ...
Tyler J. Kohler, Ian Hawes, Adrian Howkins, Lydia H. Zeglin, Mike N. Gooseff, Diane M. McKnight   +5 more
wiley   +1 more source

An MCM family protein promotes interhomolog recombination by preventing precocious intersister repair of meiotic DSBs.

PLoS Genetics, 2019
Recombinational repair of meiotic DNA double-strand breaks (DSBs) uses the homologous chromosome as a template, although the sister chromatid offers itself as a spatially more convenient substrate.
Miao Tian, Josef Loidl
doaj   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, Volume 13, Issue 12, 27 February 2026.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source