Results 121 to 130 of about 229,253 (309)

Restocking: a Guide. Herd reconstitution for African livestock keepers as part of a strategy for disaster rehabilitation.

open access: yes, 1994
A guide to planning, setting up and evaluating herd reconstitution projects in the context of disaster relief, in light of development agency experience in Kenya, Sudan, Ethiopia, Mali ...
Oxby, Clare
core  

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Blastomycosis in a renal transplant recipient: Case of immune reconstitution inflammatory syndrome

open access: yes, 2018
There are limited data on blastomycosis in solid organ transplant recipients with the subsequent development of the immune reconstitution inflammatory syndrome (IRIS).
William Geddie   +4 more
core   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

open access: yesAdvanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo   +20 more
wiley   +1 more source

Corps and division planner's guide to reconstitution operations.

open access: yes, 2019
This handbook serves as an aid to corps- and division-level staffs as they plan and prepare to conduct reconstitution operations. It provides insights into challenges the staff will face when planning reconstitution operations, outlines responsibilities ...

core  

Bundle Reconstitution Assay Dataset

open access: yes
<p>This dataset contains the raw TIRF microscopy data of bundle reconstitution assays, as well as the script used to analyze the data.</p ...
Sun, Xiaoyu   +2 more
core   +1 more source

Charting Endocrine Progenitors Across Species and Organs

open access: yesAdvanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing   +21 more
wiley   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

L'emploi d'une imprimante 3D en conservation-restauration : une application spécifique pour le Musée communal de Huy

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2007
Valérie Rousseau, Luc Engen
doaj   +1 more source

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