Results 51 to 60 of about 229,253 (309)

Post-reconstitution Stability of Telavancin with Commonly Used Diluents and Intravenous Infusion Solutions

open access: yesCurrent Therapeutic Research, 2015
Objective: The post-reconstitution chemical stability and microbial challenge hold time of nonpreserved telavancin for injection was determined using common reconstitution diluents and intravenous (IV) infusion solutions stored at room temperature with ...
Zhengtian Gu, PhD   +5 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Successful eradication of chronic myeloid leukemia in a child despite allogeneic graft rejection

open access: yesCancer Reports, 2022
Background Chronic myeloid leukemia (CML) is a rare disease in children and treated with tyrosine kinase inhibitors (TKI) and with allogeneic hematopoietic stem cell transplantation (HSCT) still in many cases.
Susanna Vuorenoja   +2 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Reconstitution of protein using SDS.

open access: yes, 2014
The size and the size distribution of reconstituted vesicles.LUV – initial liposome solutions (the same initial batch was measured at this point, which later was divided in two and processed in parallel for control and reconstitution experiments); Post ...
Andrzej Szczepaniak (665789)   +2 more
core   +1 more source

Optimized reconstitution of membrane proteins into synthetic membranes [PDF]

open access: yes, 2018
Light-driven proton pumps, such as proteorhodopsin, have been proposed as an energy source in the field of synthetic biology. Energy is required to power biochemical reactions within artificially created reaction compartments like proto-or nanocells ...
Thoma, Johannes   +11 more
core   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Comment recréer un intérieur historique en l’absence du mobilier d’origine ? L’exemple de la restitution d’une enfilade du XVIIIe siècle au château de Prangins en Suisse

open access: yesIn Situ, 2016
How does one recreate a historical interior when the original furniture has disappeared? This challenge was taken up at the Château de Prangins in Switzerland.
Helen Bieri Thomson
doaj   +1 more source

Description of modeling parameters for protein reconstitution in liposomes.

open access: yes, 2023
Description of modeling parameters for protein reconstitution in liposomes.
Melanie Ernst (6112097)   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy