Results 101 to 110 of about 3,492,533 (291)

The ‘Paths to everyday life’ (PEER) trial – a qualitative study of mechanisms of change from the perspectives of individuals with mental health difficulties participating in peer support groups led by volunteer peers

BMC Psychiatry
Background Worldwide, peers support has been shown to play a crucial role in supporting people with mental illness in their personal recovery process and return to everyday life.
Cecilie Høgh Egmose, Chalotte Heinsvig Poulsen, Siv-Therese Bogevik Bjørkedal, Lene Falgaard Eplov   +3 more
doaj   +1 more source

A single session of exercise increases connectivity in sensorimotor-related brain networks: A resting-state fMRI study in young healthy adults

Frontiers in Human Neuroscience, 2014
Habitual long term physical activity is known to have beneficial cognitive, structural and neuro-protective brain effects, but to date there is limited knowledge on whether a single session of exercise can alter the brain’s functional connectivity, as ...
Ahmad Saeed Rajab, Ahmad Saeed Rajab, David E Crane, Laura E Middleton, Laura E Middleton, Andrew eRobertson, Michelle eHampson, Bradley J MacIntosh, Bradley J MacIntosh   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Growth and protein content of Cupriavidus necator on organic acids derived from fermented grey starch

Applied Microbiology and Biotechnology
Grey starch (GS) is a byproduct of potato processing and is conventionally valorised as low-grade animal feed or for biogas generation. In this manuscript, we systematically investigate the mixed culture fermentation of GS to organic acids and their ...
Martin Struk, Myrsini Sakarika, Ángel Estévez, Ramon Ganigué, Korneel Rabaey   +4 more
doaj   +1 more source

A Pilot Field Study on Channeling Control Using Polymer Gel Prior to Gas Injection in Strong-Heterogeneity, High-Temperature, High-Salinity Reservoirs

Energies
Channeling control remains the most critical challenge in fluid injection for enhanced oil recovery (EOR). Polymer gels are widely applied in channeling control due to their capability to alter the permeability of flow channels. However, high temperature
Weidong Chen, Zhuoyan Zhu, Qingfeng Hou, Yuanyuan Wang, Xiaoling Yi, Weidong Liu   +5 more
doaj   +1 more source

New Solvent for Polyamide 66 and Its Use for Preparing a Single-Polymer Composite-Coated Fabric

International Journal of Polymer Science, 2018
Polyamides (PAs) are one of the most important engineering polymers; however, the difficulty in dissolving them hinders their applications. Formic acid (FA) is the most common solvent for PAs, but it has industrial limitations.
Mostafa Jabbari, Mikael Skrifvars, Dan Åkesson, Mohammad J. Taherzadeh   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source