Results 81 to 90 of about 3,492,533 (291)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Spontaneous Recovery [PDF]

Learning & Memory, 2004
Spontaneous recovery from extinction is one of the most basic phenomena of Pavlovian conditioning. Although it can be studied by using a variety of designs, some procedures are better than others for identifying the involvement of underlying learning processes.
openaire   +2 more sources

Multilayer biocomposite vegan leather materials derived from vegetable-tanned fungal biomass cultivated on food waste

Scientific Reports
Despite being considered a premium material, leather poses both environmental and ethical issues. Thus, sustainable alternatives such as vegan leather are in high demand. Therefore, in this study, we aimed to produce vegan leather using vegetable tannins
E. R. Kanishka B. Wijayarathna, Sofie E. Svensson, Taner Sar, Akram Zamani   +3 more
doaj   +1 more source

Perceptions of procedural justice and coercion among forensic psychiatric patients: a study protocol for a prospective, mixed-methods investigation

BMC Psychiatry, 2020
Background The risk and recovery paradigms are the dominant frameworks informing forensic mental health services and have been the focus of increasing research interest.
Alexander I. F. Simpson, Irene Boldt, Stephanie Penney, Roland Jones, Sean Kidd, Arash Nakhost, Treena Wilkie   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Ketamine for treatment resistant depression in individuals with eating disorders: a comparison study

Journal of Eating Disorders
Background Individuals with eating disorders (EDs) have an increased risk of treatment resistant depression (TRD) and treatment resistant bipolar disorder (TRBD) and a higher rate of suicidal ideation and death by suicide than individuals without EDs ...
Elizabeth Wassenaar, Dan V. Blalock, Alan Duffy, Megan Riddle, Anne Marie O’Melia, Howard Weeks, Phillip S. Mehler, Renee D. Rienecke   +7 more
doaj   +1 more source

Impact of water content on minimum miscibility pressure during CO2 flooding in high water-cut reservoirs [PDF]

E3S Web of Conferences
This study focused on the X block stratum oil, specifically addressing the application of CO2 displacement technology in enhancing oil recovery under high water content conditions.
Zhao Fajun, Guo Qinyuan, Yang Zian, Zhang Changjiang, Zhang Lei, Wang Tianyu, Xue Peiyong   +6 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source