Results 51 to 60 of about 1,893,794 (269)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Multilayer biocomposite vegan leather materials derived from vegetable-tanned fungal biomass cultivated on food waste

open access: yesScientific Reports
Despite being considered a premium material, leather poses both environmental and ethical issues. Thus, sustainable alternatives such as vegan leather are in high demand. Therefore, in this study, we aimed to produce vegan leather using vegetable tannins
E. R. Kanishka B. Wijayarathna   +3 more
doaj   +1 more source

Pigment Production by the Edible Filamentous Fungus Neurospora Intermedia

open access: yesFermentation, 2018
The production of pigments by edible filamentous fungi is gaining attention as a result of the increased interest in natural sources with added functionality in the food, feed, cosmetic, pharmaceutical and textile industries.
Rebecca Gmoser   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Impact of water content on minimum miscibility pressure during CO2 flooding in high water-cut reservoirs [PDF]

open access: yesE3S Web of Conferences
This study focused on the X block stratum oil, specifically addressing the application of CO2 displacement technology in enhancing oil recovery under high water content conditions.
Zhao Fajun   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Environmental safety and Russian central non-chernozem area agricultural adaptation to the changing weather condition problems

open access: yesRUDN Journal of Ecology and Life Safety, 2010
Farming industry of any level is usually conservative. This conservatism has to be overcome without the upcoming order. The conservatism was the major reason of the crisis during all the history of the agriculture.
V V Kovalev   +4 more
doaj  

Ketamine for treatment resistant depression in individuals with eating disorders: a comparison study

open access: yesJournal of Eating Disorders
Background Individuals with eating disorders (EDs) have an increased risk of treatment resistant depression (TRD) and treatment resistant bipolar disorder (TRBD) and a higher rate of suicidal ideation and death by suicide than individuals without EDs ...
Elizabeth Wassenaar   +7 more
doaj   +1 more source

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