Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study [PDF]
Background The effect of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) dynamics in patients with acute brain injury (ABI) remains controversial. PEEP can benefit oxygenation by promoting alveolar recruitment, but its influence on
Mariangela Pellegrini, Rafael Kawati
exaly +4 more sources
Recruitability and effect of PEEP in SARS-Cov-2-associated acute respiratory distress syndrome
Background A large proportion of patients with a SARS-Cov-2-associated respiratory failure develop an acute respiratory distress syndrome (ARDS).
François Beloncle +1 more
exaly +4 more sources
Monitoring lung recruitability during recruitment maneuvers in children with respiratory failure on ECMO using electrical impedance tomography: case report [PDF]
IntroductionCurrently, there are no clear guidelines regarding the use of recruitment maneuvers in pediatric patients with severe respiratory failure who are on extracorporeal membrane oxygenation (ECMO), nor is there consensus on how they should be ...
Jan-Christoph Clausen +9 more
exaly +4 more sources
Positive end-expiratory pressure titration in acute respiratory distress syndrome–a practical bedside algorithm [PDF]
Positive end-expiratory pressure (PEEP) selection and titration is a longstanding debate in management of mechanically ventilated patients with acute respiratory distress syndrome (ARDS).
Luís Melo +4 more
doaj +2 more sources
Impact of PEEP on V/Q mismatch according to patient position and recruitability: a clinical prospective study [PDF]
Background: High positive end-expiratory pressure (PEEP) may improve ventilation-perfusion (V/Q) mismatch in acute respiratory distress syndrome (ARDS) patients with high recruitability in supine position.
Zhiqian Zha +8 more
doaj +2 more sources
Physiology-guided personalized mechanical ventilation to prevent ventilator-induced lung injury [PDF]
Mechanical ventilation is essential for managing acute respiratory failure, yet it carries a significant risk of ventilator-induced lung injury (VILI). Lung-protective ventilation, most notably through the use of low tidal volumes, has improved outcomes ...
Raffaele Merola +7 more
doaj +2 more sources
EIT-based ventilation phenotypes of left-to-right asymmetry and ventral-to-dorsal center in PEEP titration in ARDS [PDF]
Background Ventilation distribution assessed by electrical impedance tomography (EIT) has great interests in acute respiratory distress syndrome (ARDS).
Xiaotong Sun +13 more
doaj +2 more sources
Background: Laparoscopic surgery with pneumoperitoneum increases respiratory system elastance due to the augmented intra-abdominal pressure. We aim to evaluate to which extent positive end-expiratory pressure (PEEP) is able to counteract abdominal ...
Gabriel Motta Ribeiro +2 more
exaly +3 more sources
Characterizing heterogeneity and subphenotyping acute respiratory distress syndrome with computed tomography [PDF]
Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome rather than a single disease. Patients who meet the same diagnostic criteria may differ in lung morphology, mechanical properties, biological injury, and clinical course ...
Roberta Garberi +12 more
doaj +2 more sources
Potential for Lung Recruitment Maneuvers Estimated by the Cytokines in Bronchoalveolar Lavage Fluid in Acute Respiratory Distress Syndrome [PDF]
Conclusion: Lower levels of cytokines in BALF were observed in the RM-E group. It is possible that the cytokines in BALF, especially IL-6, could be used to determine the need for RM on the basis of lung recruitability.
Minjin Shen, Jiaping Huai
doaj +2 more sources

