Results 11 to 20 of about 1,643 (122)

Radiological pattern in ARDS patients: partitioned respiratory mechanics, gas exchange and lung recruitability [PDF]

Annals of Intensive Care, 2021
Background The ARDS is characterized by different degrees of impairment in oxygenation and distribution of the lung disease. Two radiological patterns have been described: a focal and a diffuse one.
Silvia Coppola, Tommaso Pozzi, Martina Gurgitano, Alessandro Liguori, Ejona Duka, Francesca Bichi, Arianna Ciabattoni, Davide Chiumello   +7 more
doaj   +2 more sources

Induction of severe hypoxemia and low lung recruitability for the evaluation of therapeutic ventilation strategies: a translational model of combined surfactant-depletion and ventilator-induced lung injury [PDF]

Intensive Care Medicine Experimental, 2022
Background Models of hypoxemic lung injury caused by lavage-induced pulmonary surfactant depletion are prone to prompt recovery of blood oxygenation following recruitment maneuvers and have limited translational validity. We hypothesized that addition of
Emilia Boerger, Martin Russ, Philip von Platen, Mahdi Taher, Lea Hinken, Anake Pomprapa, Rainer Koebrich, Frank Konietschke, Jan Adriaan Graw, Burkhard Lachmann, Wolfgang Braun, Steffen Leonhardt, Philipp A. Pickerodt, Roland C. E. Francis   +13 more
doaj   +2 more sources

Personalised treatment of acute respiratory distress syndrome [PDF]

, 2023
This thesis describes personalised treatment of acute respiratory distress syndrome based on biomarkers and recruitability. In part 1, biomarkers, we aim to titrate the use of corticosteroids.
van der Zee, Philip
core   +13 more sources

Exploring alveolar recruitability using positive end-expiratory pressure in mice overexpressing TGF-β1: a structure–function analysis

Scientific Reports
Pre-injured lungs are prone to injury progression in response to mechanical ventilation. Heterogeneous ventilation due to (micro)atelectases imparts injurious strains on open alveoli (known as volutrauma).
Franziska Roeder, Tina Röpke, Lara-Kristin Steinmetz, Martin Kolb, Ulrich A. Maus, Bradford J. Smith, Lars Knudsen   +6 more
doaj   +2 more sources

Recruitability during General Anesthesia: Comment [PDF]

Anesthesiology
Zhaoyang Xiao
exaly   +4 more sources

Lung recruitability determines the impact of PEEP on mechanical power in ARDS [PDF]

Critical Care
Tommaso Tonetti, Domenico Luca Grieco, Antonio Maria Dell'Anna   +2 more
exaly   +2 more sources

Lung Recruitment, Individualized PEEP, and Prone Position Ventilation for COVID-19-Associated Severe ARDS: A Single Center Observational Study

Frontiers in Medicine, 2021
Background: Patients with coronavirus disease 2019 (COVID-19) may develop severe acute respiratory distress syndrome (ARDS). The aim of the study was to explore the lung recruitability, individualized positive end-expiratory pressure (PEEP), and prone ...
Ling Sang, Xia Zheng, Zhanqi Zhao, Zhanqi Zhao, Min Zhong, Li Jiang, Yongbo Huang, Xiaoqing Liu, Yimin Li, Dingyu Zhang, Dingyu Zhang   +10 more
doaj   +1 more source

Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome

Critical Care, 2022
Background In the context of acute respiratory distress syndrome (ARDS), the response to lung recruitment maneuvers (LRMs) varies considerably from one patient to another and so is difficult to predict.
Yoann Zerbib, Alexis Lambour, Julien Maizel, Loay Kontar, Bertrand De Cagny, Thierry Soupison, Thomas Bradier, Michel Slama, Clément Brault   +8 more
doaj   +1 more source

Correlation between the hysteresis of the pressure–volume curve and the recruitment-to-inflation ratio in patients with coronavirus disease 2019

Annals of Intensive Care, 2022
Background Since the response to lung recruitment varies greatly among patients receiving mechanical ventilation, lung recruitability should be assessed before recruitment maneuvers. The pressure–volume curve (PV curve) and recruitment-to-inflation ratio
Ryuichi Nakayama, Naofumi Bunya, Shinshu Katayama, Yuya Goto, Yusuke Iwamoto, Kenshiro Wada, Keishi Ogura, Naoya Yama, Shintaro Takatsuka, Masumi Kishimoto, Kanako Takahashi, Ryuichiro Kakizaki, Keigo Sawamoto, Shuji Uemura, Keisuke Harada, Eichi Narimatsu   +15 more
doaj   +1 more source

COVID-19 pneumonia: pathophysiology and management

European Respiratory Review, 2021
Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on the development of its pathophysiologic characteristics over time, and how these time-related changes determine modifications in treatment. In the emergency department:
Luciano Gattinoni, Simone Gattarello, Irene Steinberg, Mattia Busana, Paola Palermo, Stefano Lazzari, Federica Romitti, Michael Quintel, Konrad Meissner, John J. Marini, Davide Chiumello, Luigi Camporota   +11 more
doaj   +1 more source