Results 121 to 130 of about 1,921,389 (279)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Proses Penjaringan dan Penyaringan Calon Anggota Legislatif Perempuan di Kota Padang [PDF]

open access: yes, 2005
This study tried to describe the recruitment process of women candidate of Legislative Body members in Padang City handled by some popular political parties. Qualitaive approach was used in this study.
Saili, S. (Syamsir)   +1 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Penyelenggaraan Administrasi Kepegawaian di Badan Kepegawaian Daerah (BKD) Kabupaten Kepulauan Sula [PDF]

open access: yes, 2016
This study aims to determine how the administration of the Organization in terms of personnel,especially in the district of Sulu Islands Regional Employment Board.This study used qualitative methods. The informants were 10 officers / employees at BKD are:
Kiyai, B. (Burhanuddin)   +2 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Recruitment and Selection Process Using Artificial Intelligence: How Do Candidates React?

open access: yesAdministrative Sciences
This study aimed to study the association between organizational attractiveness, intrinsic motivation, perceived novelty, trust in the process, and the intention to apply, engage, and finish an artificial intelligence recruitment and selection process ...
Nuno Ligeiro, Ivo Dias, Ana Moreira
doaj   +1 more source

Understanding the Organization, Operation, and Victimization Process of Labor Trafficking in the United States [PDF]

open access: yes, 2014
This study examines the organization, operation, and victimization process of labor trafficking across multiple industries in the United States. It examines labor trafficking victim abuse and exploitation along a continuum, from victims' recruitment for ...
Amy Farrell   +8 more
core  

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