Results 21 to 30 of about 4,894,740 (406)

Development and validation of MRI‐based deep learning models for prediction of microsatellite instability in rectal cancer

Cancer Medicine, 2021
Microsatellite instability (MSI) predetermines responses to adjuvant 5‐fluorouracil and immunotherapy in rectal cancer and serves as a prognostic biomarker for clinical outcomes.
Wei Zhang, Hongkun Yin, Zixing Huang, Jian Zhao, Haiming Zheng, Du He, Mou Li, Weixiong Tan, Song Tian, B. Song   +9 more
semanticscholar   +1 more source

Imaging of rectal cancer [PDF]

Der Radiologe, 2019
Abstract International guidelines dictate that magnetic resonance imaging (MRI) should be part of the primary standard work up of patients with rectal cancer because MRI can accurately identify the main risk factors for local recurrence and stratify patients into a differentiated treatment.
Regina G. H. Beets-Tan, Regina G. H. Beets-Tan, Regina G. H. Beets-Tan, J. Boot, J. Boot, F. Gomez-Munoz   +5 more
openaire   +3 more sources

Impact of Diabetes on Oncologic Outcome of Colorectal Cancer Patients: Colon vs. Rectal Cancer [PDF]

, 2013
Background: To evaluate the impact of diabetes on outcomes in colorectal cancer patients and to examine whether this association varies by the location of tumor (colon vs. rectum).
Chu, Sang Hui, Jeon, Justin Y., Jeong, Duck Hyoun, Kim, Nam Kyu, Lee, Ji-Won, Lee, Mi Kyung, Ligibel, Jennifer A., Meyerhardt, Jeffrey A, Park, Ji-Hye, Park, Min Geun, Sato, Kaori   +10 more
core   +8 more sources

Comprehensive Analysis of miRNA-Mediated Regulatory Network and Identification of Prognosis Biomarkers in Rectal Cancer

Frontiers in Genetics, 2022
Rectal cancer is a malignant tumor with poor prognosis. Identification of prognostic biomarkers is needed to improve overall survival of rectal cancer patients. Here, we firstly identified miR-20a-5p significantly classifying high-risk group and low-risk
Tingting Tang, Sisi Yu, Zekai Song, Xiaofu Pan, Fang Xu, Yanke Wu, Liang Zhang   +6 more
doaj   +1 more source

Rectal stenosis due to solitary pelvic recurrence of hilar cholangiocarcinoma

JGH Open, 2020
An 85‐year‐old woman was admitted to a hospital with abdominal pain. Five years prior to admission, she had a history of hilar cholangiocarcinoma of pStage IIIC. Contrast‐enhanced computed tomography showed a mass between the rectum and uterus as well as
Ikuma Shioi, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Hitoshi Hino, Shoichi Manabe, Daisuke Aizawa   +6 more
doaj   +1 more source

Diagnostic value of computed tomography (CT) and positron emission tomography (PET) for paraaortic lymph node metastasis from left-sided colon and rectal cancer

Asian Journal of Surgery, 2020
Summary: Background/objective: Paraaortic lymph node (PALN) metastasis influences treatment strategy for colorectal cancer. The aims of this study were to elucidate the diagnostic value of computed tomography (CT) and positron emission tomography (PET ...
Nozomu Nakai, Tomohiro Yamaguchi, Yusuke Kinugasa, Akio Shiomi, Hiroyasu Kagawa, Yushi Yamakawa, Masakatsu Numata, Akinobu Furutani, Yusuke Yamaoka, Shoichi Manabe, Akihiro Sawada   +10 more
doaj   +1 more source

SNHG17 Serves as an Oncogenic lncRNA by Regulating the miR-361-3p/STC2 Axis in Rectal Cancer

Frontiers in Genetics, 2021
Long noncoding RNA (lncRNA) have been reported to be crucial regulators for carcinogenesis, including rectal cancer. This work aimed to explore the roles and associated mechanisms of small nucleolar RNA host gene 17 (SNHG17) in rectal cancer.
Fuda Huang, Hua Li, Zebang Qin, Anmin Wang, Ya Zhang, Junyu Guo, Mingwei Wei, Houji Guo, Jian Pu   +8 more
doaj   +1 more source

Total Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer

JAMA Network Open, 2020
Key Points Question Is total neoadjuvant therapy (TNT) associated with improved outcomes when compared with standard concurrent chemoradiotherapy followed by surgery and adjuvant chemotherapy (CRT plus A) for locally advanced rectal cancer?
A. Kasi, Saqib Abbasi, S. Handa, R. Al-Rajabi, A. Saeed, J. Baranda, Weijing Sun   +6 more
semanticscholar   +1 more source

M6A “Writer” Gene METTL14: A Favorable Prognostic Biomarker and Correlated With Immune Infiltrates in Rectal Cancer

Frontiers in Oncology, 2021
Rectal cancer (RC) is the leading cause of tumor-related death among both men and women. The efficacy of immunotherapy for rectal cancer is closely related to the immune infiltration level.
Changjing Cai, Changjing Cai, Jie Long, Jie Long, Jie Long, Qiaoqiao Huang, Qiaoqiao Huang, Ying Han, Ying Han, Yinghui Peng, Yinghui Peng, Cao Guo, Cao Guo, Shanshan Liu, Yihong Chen, Yihong Chen, Edward Shen, Kexin Long, Xinwen Wang, Xinwen Wang, Jian Yu, Hong Shen, Hong Shen, Hong Shen, Shan Zeng, Shan Zeng   +25 more
doaj   +1 more source

Comprehensive molecular characterization of human colon and rectal cancer

Nature, 2012
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression.
D. Muzny, M. Bainbridge, K. Chang, H. Dinh, J. Drummond, G. Fowler, C. Kovar, L. Lewis, M. Morgan, I. Newsham, J. Reid, J. Santibanez, E. Shinbrot, L. Treviño, Yuan-qing Wu, Min Wang, P. Gunaratne, L. Donehower, C. Creighton, D. Wheeler, R. Gibbs, M. Lawrence, Douglas Voet, R. Jing, K. Cibulskis, A. Sivachenko, P. Stojanov, A. McKenna, E. Lander, S. Gabriel, L. Ding, R. Fulton, D. Koboldt, T. Wylie, Jason R. Walker, D. Dooling, L. Fulton, K. Delehaunty, C. Fronick, Ryan T. Demeter, E. Mardis, R. Wilson, Andy Chu, Hye-Jung E. Chun, A. Mungall, E. Pleasance, A. G. Robertson, D. Stoll, M. Balasundaram, I. Birol, Y. Butterfield, E. Chuah, R. Coope, Noreen Dhalla, R. Guin, Carrie Hirst, M. Hirst, R. Holt, Darlene Lee, H. Li, Michael Mayo, Richard A. Moore, J. Schein, Jared R. Slobodan, Angela Tam, N. Thiessen, R. Varhol, Thomas Zeng, Yongjun Zhao, Steven J. M. Jones, M. Marra, A. Bass, A. Ramos, G. Saksena, A. Cherniack, S. Schumacher, B. Tabak, S. Carter, Nam Pho, Huy L. Nguyen, R. Onofrio, A. Crenshaw, K. Ardlie, R. Beroukhim, W. Winckler, M. Meyerson, A. Protopopov, Angela Hadjipanayis, E. Lee, Ruibin Xi, Lixing Yang, X. Ren, N. Sathiamoorthy, Peng-Chieh Chen, Psalm S. Haseley, Yonghong Xiao, Semin Lee, J. Seidman, L. Chin, P. Park, R. Kucherlapati, J. Auman, K. Hoadley, Ying Du, M. Wilkerson, Yan Shi, C. Liquori, S. Meng, Ling Li, Yidi J. Turman, M. D. Topal, Donghui Tan, S. Waring, Elizabeth Buda, Jesse L. Walsh, Corbin D. Jones, P. Mieczkowski, Darshan Singh, Junyuan Wu, Anisha Gulabani, Peter Dolina, T. Bodenheimer, A. Hoyle, J. Simons, Matthew G. Soloway, Lisle E. Mose, S. Jefferys, S. Balu, Brian D. O’Connor, J. Prins, Derek Y. Chiang, D. Hayes, C. Perou, T. Hinoue, D. Weisenberger, D. Maglinte, F. Pan, B. Berman, D. V. Berg, Hui Shen, T. Triche, S. Baylin, P. Laird, G. Getz, M. Noble, Doug Voat, Nils Gehlenborg, D. Dicara, Juinhua Zhang, Hailei Zhang, Chang-Jiun Wu, Spring Yingchun Liu, S. Shukla, Lihua Zhou, Pei Lin, R. Park, Marc-Danie Nazaire, James Robinson, H. Thorvaldsdóttir, J. Mesirov, V. Thorsson, Sheila M. Reynolds, Brady Bernard, R. Kreisberg, Jake Lin, L. Iype, Ryan Bressler, Timo Erkkilä, M. Gundapuneni, Yuexin Liu, Adam Norberg, Thomas Robinson, Da Yang, Wei Zhang, I. Shmulevich, J. J. Ronde, N. Schultz, E. Cerami, G. Ciriello, A. P. Goldberg, Benjamin E. Gross, A. Jacobsen, Jianjiong Gao, B. Kaczkowski, Rileen Sinha, B. A. Aksoy, Yevgeniy Antipin, B. Reva, R. Shen, B. Taylor, M. Ladanyi, C. Sander, Rehan Akbani, Nianxiang Zhang, B. Broom, Tod D. Casasent, A. Unruh, Chris Wakefield, S. Hamilton, R. Cason, K. Baggerly, J. Weinstein, D. Haussler, C. Benz, Joshua M. Stuart, S. Benz, J. Z. Sanborn, Charles J. Vaske, Jingchun Zhu, C. Szeto, G. Scott, C. Yau, S. Ng, Theodore Goldstein, K. Ellrott, E. Collisson, A. E. Cozen, D. Zerbino, C. Wilks, Brian Craft, P. Spellman, R. Penny, T. Shelton, M. Hatfield, S. Morris, P. Yena, C. Shelton, M. Sherman, J. Paulauskis, J. Gastier-Foster, Jay Bowen, N. Ramirez, Aaron D. Black, R. Pyatt, L. Wise, P. White, M. Bertagnolli, Jennifer Brown, T. Chan, Gerald C. Chu, Christine Czerwinski, F. Denstman, R. Dhir, A. Dörner, C. Fuchs, J. Guillem, M. Iacocca, H. Juhl, Andrew Kaufman, B. Kohl, X. Le, M. C. Mariano, Elizabeth N. Medina, M. Meyers, G. Nash, P. Paty, N. Petrelli, B. Rabeno, W. Richards, D. Solit, P. Swanson, L. Temple, J. Tepper, Richard A. Thorp, E. Vakiani, M. Weiser, J. Willis, G. Witkin, Z. Zeng, M. Zinner, C. Zornig, M. Jensen, R. Sfeir, A. Kahn, A. Chu, Prachi Kothiyal, Zhining Wang, E. Snyder, J. Pontius, T. Pihl, Brenda Ayala, M. Backus, Jessica L Walton, J. Whitmore, J. Baboud, D. Berton, M. Nicholls, Deepak Srinivasan, R. Raman, Stanley Girshik, Peter A. Kigonya, S. Alonso, Rashmi N. Sanbhadti, S. Barletta, J. Greene, D. Pot, K. Shaw, Laura A. L. Dillon, K. Buetow, Tanja Davidsen, John A. Demchok, G. Eley, M. Ferguson, P. Fielding, C. Schaefer, Margi Sheth, Liming Yang, M. Guyer, B. Ozenberger, Jacqueline D. Palchik, Jane L. Peterson, H. Sofia, E. Thomson   +312 more
semanticscholar   +1 more source