Results 31 to 40 of about 5,235,363 (361)

Comprehensive Molecular Characterization of Human Colon and Rectal Cancer

Nature, 2012
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression.
D. Muzny, M. Bainbridge, Kyle Chang, H. Dinh, J. Drummond, G. Fowler, C. Kovar, L. Lewis, M. Morgan, I. Newsham, J. Reid, J. Santibanez, E. Shinbrot, L. Treviño, Yuan-qing Wu, Min Wang, P. Gunaratne, L. Donehower, C. Creighton, D. Wheeler, R. Gibbs, M. Lawrence, D. Voet, R. Jing, K. Cibulskis, A. Sivachenko, P. Stojanov, A. McKenna, E. Lander, S. Gabriel, L. Ding, R. Fulton, D. Koboldt, T. Wylie, Jason R. Walker, D. Dooling, L. Fulton, K. D. Delehaunty, Catrina C. Fronick, Ryan T. Demeter, E. Mardis, R. Wilson, Andy Chu, Hye-Jung E. Chun, A. Mungall, E. Pleasance, A. G. Robertson, D. Stoll, M. Balasundaram, I. Birol, Y. Butterfield, E. Chuah, R. Coope, Noreen Dhalla, R. Guin, Carrie Hirst, M. Hirst, R. Holt, Darlene Lee, H. Li, Michael Mayo, Richard A. Moore, J. Schein, Jared R. Slobodan, Angela Tam, N. Thiessen, R. Varhol, Thomas Zeng, Yongjun Zhao, Steven J. M. Jones, M. Marra, A. Bass, A. Ramos, G. Saksena, A. Cherniack, S. Schumacher, B. Tabak, S. Carter, Nam Pho, Huy L. Nguyen, R. Onofrio, A. Crenshaw, K. Ardlie, R. Beroukhim, W. Winckler, M. Meyerson, A. Protopopov, Angela Hadjipanayis, E. Lee, Ruibin Xi, Lixing Yang, X. Ren, N. Sathiamoorthy, Peng-Chieh Chen, Psalm S. Haseley, Yonghong Xiao, Semin Lee, J. Seidman, L. Chin, P. Park, R. Kucherlapati, J. Auman, K. Hoadley, Ying Du, M. Wilkerson, Yan Shi, C. Liquori, S. Meng, Ling Li, Yidi J. Turman, M. D. Topal, Donghui Tan, S. Waring, Elizabeth Buda, Jesse L. Walsh, Corbin D. Jones, P. Mieczkowski, Darshan Singh, Junyuan Wu, Anisha Gulabani, Peter Dolina, T. Bodenheimer, A. Hoyle, J. Simons, Matthew G. Soloway, Lisle E. Mose, S. Jefferys, S. Balu, Brian O’Connor, J. Prins, Derek Y. Chiang, D. Hayes, C. Perou, T. Hinoue, D. Weisenberger, D. Maglinte, F. Pan, B. Berman, D. V. Berg, Hui Shen, T. Triche, S. Baylin, P. Laird, G. Getz, M. Noble, Doug Voat, Nils Gehlenborg, D. Dicara, Juinhua Zhang, Hailei Zhang, Chang-Jiun Wu, S. Y. Liu, S. Shukla, Lihua Zhou, Pei Lin, R. Park, Marc-Danie Nazaire, James Robinson, H. Thorvaldsdóttir, J. Mesirov, V. Thorsson, Sheila M. Reynolds, Brady Bernard, R. Kreisberg, Jake Lin, L. Iype, Ryan Bressler, Timo Erkkilä, M. Gundapuneni, Yuexin Liu, Adam Norberg, Thomas Robinson, Da Yang, Wei Zhang, I. Shmulevich, J. J. Ronde, N. Schultz, E. Cerami, G. Ciriello, A. Goldberg, Benjamin E. Gross, A. Jacobsen, Jianjiong Gao, B. Kaczkowski, Rileen Sinha, B. A. Aksoy, Y. Antipin, B. Reva, R. Shen, B. Taylor, M. Ladanyi, C. Sander, Rehan Akbani, Nianxiang Zhang, B. Broom, Tod D. Casasent, A. Unruh, Chris Wakefield, S. Hamilton, R. Cason, K. Baggerly, J. Weinstein, D. Haussler, C. Benz, Joshua M. Stuart, S. Benz, J. Z. Sanborn, Charles J. Vaske, Jingchun Zhu, C. Szeto, G. Scott, C. Yau, S. Ng, Theodore Goldstein, K. Ellrott, E. Collisson, A. E. Cozen, D. Zerbino, C. Wilks, B. Craft, P. Spellman, R. Penny, T. Shelton, M. Hatfield, S. Morris, P. Yena, C. Shelton, M. Sherman, J. Paulauskis, J. Gastier-Foster, Jay Bowen, N. Ramirez, Aaron D. Black, R. Pyatt, L. Wise, P. White, M. Bertagnolli, Jennifer Brown, T. Chan, Gerald C. Chu, Christine Czerwinski, F. Denstman, R. Dhir, A. Dörner, C. Fuchs, J. Guillem, M. Iacocca, H. Juhl, Andrew Kaufman, B. Kohl, X. Le, M. C. Mariano, Elizabeth N. Medina, M. Meyers, G. Nash, P. Paty, N. Petrelli, B. Rabeno, W. Richards, D. Solit, P. Swanson, L. Temple, J. Tepper, Richard A. Thorp, E. Vakiani, M. Weiser, J. Willis, G. Witkin, Z. Zeng, M. Zinner, C. Zornig, M. Jensen, R. Sfeir, A. Kahn, A. Chu, Prachi Kothiyal, Zhining Wang, E. Snyder, J. Pontius, T. Pihl, B. Ayala, M. Backus, Jessica L Walton, J. Whitmore, J. Baboud, D. Berton, M. Nicholls, D. Srinivasan, R. Raman, Stanley Girshik, Peter A. Kigonya, S. Alonso, Rashmi N. Sanbhadti, S. Barletta, J. Greene, D. Pot, K. Shaw, Laura A. L. Dillon, K. Buetow, Tanja Davidsen, J. Demchok, G. Eley, M. Ferguson, P. Fielding, C. Schaefer, Margi Sheth, Liming Yang, M. Guyer, B. Ozenberger, Jacqueline D. Palchik, Jane L. Peterson, H. Sofia, E. Thomson   +312 more
semanticscholar   +1 more source

Feasibility and morbidity of combined hyperthermia and radiochemotherapy in recurrent rectal cancer - Preliminary results [PDF]

, 2003
Background: The local recurrence rate of colorectal cancer has been significantly reduced due to the use of combined radiochemotherapy. Despite this improvement regarding locally advanced tumour recurrences, the treatment strategy for pre-treated ...
Schaffer, P.M., Ertl-Wagner, Birgit, M. Schaffer, E. Dühmke, P.M. Schaffer, R.D. Issels, Pachmann, S., Abdel-Rahman, Sultan, S. Abdel-Rahman, Abdel-Rahman, S., Ertl-Wagner, B., Krych, M., Issels, Rolf-Dieter, Dühmke, E., B. Ertl-Wagner, Schaffer, Pamela Manuela, M. Krych, S. Pachmann, Schäffer, M., Issels, R.D., Dühmke, Eckhart, Schaffer, Moshe   +21 more
core   +1 more source

Rectal stenosis due to solitary pelvic recurrence of hilar cholangiocarcinoma

JGH Open, 2020
An 85‐year‐old woman was admitted to a hospital with abdominal pain. Five years prior to admission, she had a history of hilar cholangiocarcinoma of pStage IIIC. Contrast‐enhanced computed tomography showed a mass between the rectum and uterus as well as
Ikuma Shioi, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Hitoshi Hino, Shoichi Manabe, Daisuke Aizawa   +6 more
doaj   +1 more source

Diagnostic value of computed tomography (CT) and positron emission tomography (PET) for paraaortic lymph node metastasis from left-sided colon and rectal cancer

Asian Journal of Surgery, 2020
Summary: Background/objective: Paraaortic lymph node (PALN) metastasis influences treatment strategy for colorectal cancer. The aims of this study were to elucidate the diagnostic value of computed tomography (CT) and positron emission tomography (PET ...
Nozomu Nakai, Tomohiro Yamaguchi, Yusuke Kinugasa, Akio Shiomi, Hiroyasu Kagawa, Yushi Yamakawa, Masakatsu Numata, Akinobu Furutani, Yusuke Yamaoka, Shoichi Manabe, Akihiro Sawada   +10 more
doaj   +1 more source

Comprehensive Analysis of miRNA-Mediated Regulatory Network and Identification of Prognosis Biomarkers in Rectal Cancer

Frontiers in Genetics, 2022
Rectal cancer is a malignant tumor with poor prognosis. Identification of prognostic biomarkers is needed to improve overall survival of rectal cancer patients. Here, we firstly identified miR-20a-5p significantly classifying high-risk group and low-risk
Tingting Tang, Sisi Yu, Zekai Song, Xiaofu Pan, Fang Xu, Yanke Wu, Liang Zhang   +6 more
doaj   +1 more source

Developing Nurses’ Performance Guidelines for Patients with Rectal Cancer Undergoing Radiotherapy [PDF]

Egyptian Journal of Health Care, 2022
Background: Rectal cancer is one of the most common forms of cancer and one of the top cancer killers. One of the modalities treatment is radiotherapy that causes fewer side effects as fatigue, skin reactions, gastrointestinal disturbance, rectal ...
Zeinab Hussein Baker, Mohamed Mostafa Whman, Dalia Abdallah Abdelatief, Lamiaa Gamal Khudary   +3 more
doaj   +1 more source

NCCN Guidelines Insights: Rectal Cancer, Version 6.2020.

The Journal of the National Comprehensive Cancer Network, 2020
The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the ...
A. Benson, A. Venook, M. Al-Hawary, M. Arain, Yi-Jen Chen, K. Ciombor, S. Cohen, H. Cooper, D. Deming, I. Garrido-Laguna, J. Grem, A. Gunn, S. Hoffe, J. Hubbard, S. Hunt, Natalie N. Kirilcuk, S. Krishnamurthi, W. Messersmith, J. Meyerhardt, E. Miller, M. Mulcahy, Steven J. Nurkin, M. Overman, A. Parikh, Hitendra R. H. Patel, K. Pedersen, L. Saltz, C. Schneider, D. Shibata, J. Skibber, C. Sofocleous, E. Stoffel, E. Stotsky-Himelfarb, C. Willett, Alyse Johnson-Chilla, Lisa A. Gurski   +35 more
semanticscholar   +1 more source

Development and validation of MRI‐based deep learning models for prediction of microsatellite instability in rectal cancer

Cancer Medicine, 2021
Microsatellite instability (MSI) predetermines responses to adjuvant 5‐fluorouracil and immunotherapy in rectal cancer and serves as a prognostic biomarker for clinical outcomes.
Wei Zhang, Hongkun Yin, Zixing Huang, Jian Zhao, Haiming Zheng, Du He, Mou Li, Weixiong Tan, Song Tian, B. Song   +9 more
semanticscholar   +1 more source

Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]

, 2002
Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Wilkowski, R., Schaffer, Pamela Manuela, Thoma, M., Dühmke, Eckhart, Schaffer, Moshe   +4 more
core   +1 more source

M6A “Writer” Gene METTL14: A Favorable Prognostic Biomarker and Correlated With Immune Infiltrates in Rectal Cancer

Frontiers in Oncology, 2021
Rectal cancer (RC) is the leading cause of tumor-related death among both men and women. The efficacy of immunotherapy for rectal cancer is closely related to the immune infiltration level.
Changjing Cai, Changjing Cai, Jie Long, Jie Long, Jie Long, Qiaoqiao Huang, Qiaoqiao Huang, Ying Han, Ying Han, Yinghui Peng, Yinghui Peng, Cao Guo, Cao Guo, Shanshan Liu, Yihong Chen, Yihong Chen, Edward Shen, Kexin Long, Xinwen Wang, Xinwen Wang, Jian Yu, Hong Shen, Hong Shen, Hong Shen, Shan Zeng, Shan Zeng   +25 more
doaj   +1 more source