Results 51 to 60 of about 5,235,363 (361)

MicroRNA in rectal cancer

World Journal of Gastrointestinal Oncology, 2016
In rectal cancer, one of the most common cancers worldwide, the proper staging of the disease determines the subsequent therapy. For those with locally advanced rectal cancer, a neoadjuvant chemoradiotherapy (CRT) is recommended before any surgery.
Azizian, Azadeh, Gruber, Jens, Ghadimi, B Michael, Gaedcke, Jochen   +3 more
openaire   +3 more sources

IGRT in rectal cancer [PDF]

Acta Oncologica, 2008
To date, no great interest has been shown in the clinical implementation of recent Image-guided radiation therapy (IGRT) modalities in rectal cancer since only a few studies have been published on this issue. This may be explained by the fact that with current treatment modalities locoregional recurrences are already very low (around 10%).
Edy, Ippolito, Ine, Mertens, Karin, Haustermans, Maria Antonietta, Gambacorta, Danilo, Pasini, Vincenzo, Valentini   +5 more
openaire   +3 more sources

Relationship between quantitative analysis parameters of DCE-MRI and microangiogenesis in rectal cancer [PDF]

Zhongguo aizheng zazhi
Background and purpose: Tumor microangiogenesis is an important basis for tumor growth and metastasis, and its characteristics include angiogenesis, increased vascular permeability and abnormal capillary structure.
SONG Dan, CHAI Yaxin, GE Yanping
doaj   +3 more sources

Identification of genes inducing resistance to ionizing radiation in human rectal cancer cell lines: re-sensitization of radio-resistant rectal cancer cells through down regulating NDRG1

BMC Cancer, 2018
Background Resistance to preoperative radiotherapy is a major clinical problem in the treatment for locally advanced rectal cancer. The role of NDRG1 in resistance to ionizing radiation in rectal cancer has not been fully elucidated.
Soon-Chan Kim, Young-Kyoung Shin, Ye-Ah Kim, Sang-Geun Jang, Ja-Lok Ku   +4 more
doaj   +1 more source

Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study.

The Lancet, 2018
BACKGROUND The strategy of watch and wait (W&W) in patients with rectal cancer who achieve a complete clinical response (cCR) after neoadjuvant therapy is new and offers an opportunity for patients to avoid major resection surgery.
M. V. D. Valk, D. Hilling, E. Bastiaannet, E. Kranenbarg, G. Beets, N. Figueiredo, A. Habr-Gama, R. Perez, A. Renehan, C. Velde, M. Ahlberg, A. Appelt, O. Asoglu, M. Bär, R. Barroca, R. Beets-Tan, E. Belgers, Robbert J. I. Bosker, S. Breukink, K. Bujko, Carlos Carvalho, Christopher R Cunningham, B. Creavin, A. D'Hoore, J. Gérard, S. Gollins, C. Hoff, F. Holman, B. Hupkens, S. Iseas, A. Jakobsen, A. Keshvari, S. Koopal, M. Kusters, M. Langheinrich, J. Leijtens, M. Maas, L. Malcomson, Z. Z. Mamedli, A. Martling, K. Matzel, J. Melenhorst, M. Morici, S. Murad-Regadas, S. O'dwyer, K. Peeters, I. Rosa, G. Rossi, H. Rutten, F. Loria, M. V. D. Sande, G. Julião, M. Saunders, A. Myint, H. Sluis, R. Schiappa, N. Scott, J. Stoot, A. K. Talsma, I. Terrasson, H. Tokmak, C. Vaccaro, Alexander L Vahrmeijer, D. Wasowicz, H. L. Westreenen, D. Winter, A. Wolthuis, D. Zimmerman   +67 more
semanticscholar   +1 more source

MRI cT1–2 rectal cancer staging accuracy: a population‐based study

British Journal of Surgery, 2020
Adequate MRI‐based staging of early rectal cancers is essential for decision‐making in an era of organ‐conserving treatment approaches. The aim of this population‐based study was to determine the accuracy of routine daily MRI staging of early rectal ...
R. Detering, S. E. Oostendorp, V. Meyer, S. Dieren, A. Bos, J. Dekker, O. Reerink, J.H.T.M. van Waesberghe, C. Marijnen, Leon M G Moons, Regina G. H. Beets-Tan, Roel Hompes, H. L. Westreenen, P. J. Tanis, J. Tuynman   +14 more
semanticscholar   +1 more source

Risk factors for delay in symptomatic presentation: a survey of cancer patients [PDF]

, 2014
Background: Delay in symptomatic presentation leading to advanced stage at diagnosis may contribute to poor cancer survival. To inform public health approaches to promoting early symptomatic presentation, we aimed to identify risk factors for delay in ...
F Warburton, M A Richards, Richards, M.A., L J L Forbes, A J Ramirez, Forbes, L. J. L., Ramirez, A.J., Richards, M. A., Forbes, L.J.L., Ramirez, A. J., Warburton, F.   +10 more
core   +1 more source

Colon and rectal cancer survival in seven high-income countries 2010–2014: variation by age and stage at diagnosis (the ICBP SURVMARK-2 project)

Gut, 2020
Objectives As part of the International Cancer Benchmarking Partnership (ICBP) SURVMARK-2 project, we provide the most recent estimates of colon and rectal cancer survival in seven high-income countries by age and stage at diagnosis.
M. Araghi, M. Arnold, M. Rutherford, M. Guren, C. Cabasag, A. Bardot, J. Ferlay, H. Tervonen, L. Shack, R. Woods, N. Saint-Jacques, P. De, C. McClure, G. Engholm, A. Gavin, E. Morgan, P. Walsh, C. Jackson, G. Porter, B. Møller, O. Bucher, Michael Eden, D. O’Connell, F. Bray, I. Soerjomataram   +24 more
semanticscholar   +1 more source

Determination of prognostic factors in early rectal cancer and the implications for rectal preservation surgery

, 2020
Local excision of early rectal cancer has benefits to patients, with reduced morbidity compared to radical surgery, but carries a higher risk of local recurrence.
Jones, Helen JS
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source