Results 61 to 70 of about 3,176,177 (307)

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah, Martha E. Stewart, Nathan Maassel, James P. Stevens, Claudia R. Morris, Chris A. Rees   +5 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer

Annals of Gastroenterological Surgery
Aim To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long‐term outcomes following curative resection for pathological stage III colorectal cancer (CRC).
Akitoshi Nankaku, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Shoichi Manabe, Takuma Oishi, Kiyoshi Tone, Akifumi Notsu, Yusuke Kinugasa   +8 more
doaj   +1 more source

Recent advances in minimally invasive colorectal cancer surgery [PDF]

, 2002
Laparoscopy has improved surgical treatment of various diseases due to its limited surgical trauma and has developed as an interesting therapeutic alternative for the resection of colorectal cancer.
Wichmann, Mathias W., Rau, H. G., Schildberg, Friedrich Wilhelm, Angele, M. K., Meyer, G., H.G. Rau, F.-W. Schildberg, G. Meyer, M.W. Wichmann, M.K. Angele   +9 more
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Patient delay in colorectal cancer patients: associations with rectal bleeding and thoughts about cancer.

PLoS ONE, 2013
Rectal bleeding is considered to be an alarm symptom of colorectal cancer. However, the symptom is seldom reported to the general practitioner and it is often assumed that patients assign the rectal bleeding to benign conditions.
Anette F Pedersen, Rikke P Hansen, Peter Vedsted   +2 more
doaj   +1 more source

A case of local recurrence of T1 rectal cancer 10 years after transanal excision

, 2018
2018-02We report a case of a patient with T1 rectal cancer, which recurred locally after 10 years from the primary operation. A 78-year-old woman was diagnosed with rectal cancer. Transanal excision (TAE) was performed in December 2006.
Hosoi, Takahiro, Tsutsuyama, Masayuki, Komori, Koji, Uchino, Tairin, Tanaka, Hideharu, Oshiro, Taihei, Ouchi, Akira, Shimizu, Yasuhiro, Kinoshita, Takashi, Ito, Yuichi, Shigeyoshi, Itaru, Natsume, Seiji, Hayashi, Daisuke, Kunitomo, Aina, An, Byonggu, Abe, Tetsuya, Uemura, Norihisa, Higaki, Eiji, Senda, Yoshiki, Misawa, Kazunari, Ito, Seiji, Akazawa, Tomoyuki   +21 more
core   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Testing Machine Learning Models to Predict Postoperative Ileus after Colorectal Surgery

Current Oncology
Background: Postoperative ileus (POI) is a common complication after colorectal surgery, leading to increased hospital stay and costs. This study aimed to explore patient comorbidities that contribute to the development of POI in the colorectal surgical ...
Garry Brydges, George J. Chang, Tong J. Gan, Tsuyoshi Konishi, Vijaya Gottumukkala, Abhineet Uppal   +5 more
doaj   +1 more source

Incidence and Pattern of Nodal Metastasis in Colon and Rectal Cancer: a Study of 1012 Cases from Thailand

Siriraj Medical Journal, 2020
Objective: Lymph node (LN) metastasis is a key to determine prognosis and adjuvant treatment for resectable colorectal cancer. This study aimed to determine and compare the incidence and pattern of LN metastasis between colon cancer and rectal cancer ...
Varut Lohsiriwat , Chayudee Rungteeranont , Napat Saigosoom   +2 more
doaj   +1 more source