Results 81 to 90 of about 4,845,209 (387)

Clinical significance of Neutrophil gelatinase-associated lipocalin(NGAL) expression in primary rectal cancer

BMC Cancer, 2009
Background Emerging evidence has demonstrated that Neutrophil gelatinase-associated lipocalin (NGAL) is up-regulated in multiple malignancies, including oesophagus cancer, and plays a critical role in tumorigenesis and progression.
Guo Gui-Long, Wang Ou-Chen, Yang Guan-Gen, Zhou Su-Mei, Zhang Xiao-Hua, Zhang Ying, Zhang Xiu-Feng, Yang Gao-Yi, Hu Xiao-Qu   +8 more
doaj   +1 more source

Surgical treatment of stage IV colorectal cancer with synchronous liver metastases : a systematic review and network meta-analysis

, 2020
Background: The ideal treatment approach for colorectal cancer (CRC) with synchronous liver metastases (SCRLM) remains debated. We performed a network meta-analysis (NMA) comparing the 'bowel-first' approach (BFA), simultaneous resection (SIM), and the ...
Berardi, Giammauro, Ceelen, Wim, Ghiasloo, Mohammad, Pavlenko, Diana, Troisi, Roberto, Uyttebroek, Ortwin, Van Langenhove, Zoé, Verhaeghe, Marzia   +7 more
core   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer

Annals of Gastroenterological Surgery
Aim To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long‐term outcomes following curative resection for pathological stage III colorectal cancer (CRC).
Akitoshi Nankaku, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Shoichi Manabe, Takuma Oishi, Kiyoshi Tone, Akifumi Notsu, Yusuke Kinugasa   +8 more
doaj   +1 more source

Patient delay in colorectal cancer patients: associations with rectal bleeding and thoughts about cancer.

PLoS ONE, 2013
Rectal bleeding is considered to be an alarm symptom of colorectal cancer. However, the symptom is seldom reported to the general practitioner and it is often assumed that patients assign the rectal bleeding to benign conditions.
Anette F Pedersen, Rikke P Hansen, Peter Vedsted   +2 more
doaj   +1 more source

Ultrasound-guided trans-rectal high-intensity focused ultrasound (HIFU) for advanced cervical cancer ablation is feasible: a case report. [PDF]

, 2015
High-intensity focused ultrasound (HIFU) is an ablative treatment undergoing assessment for the treatment of benign and malignant disease. We describe the first reported intracavitary HIFU ablation for recurrent, unresectable and symptomatic cervical ...
Abel, M, Abel, P, Ahmed, H, Chen, M, Gedroyc, W, Leen, E, Monzon, L, Park, E, Price, P, Wasan, H   +9 more
core   +1 more source

Disease-free Survival and Local Recurrence for Laparoscopic Resection Compared With Open Resection of Stage II to III Rectal Cancer: Follow-up Results of the ACOSOG Z6051 Randomized Controlled Trial

Annals of Surgery, 2019
Objective: To determine the disease-free survival (DFS) and recurrence after the treatment of patients with rectal cancer with open (OPEN) or laparoscopic (LAP) resection.
J. Fleshman, M. Branda, D. Sargent, A. Boller, Virgilio V George, M. Abbas, W. Peters, Dipen C. Maun, G. Chang, A. Herline, A. Fichera, M. Mutch, S. Wexner, M. Whiteford, J. Marks, Elisa Birnbaum, D. Margolin, D. Larson, P. Marcello, M. Posner, T. Read, J. Monson, S. Wren, P. Pisters, H. Nelson   +24 more
semanticscholar   +1 more source

Stretchable, Multiplexed, and Bimodal Sensing Electronic Armor for Colonoscopic Continuum Robot Enhanced by Triboelectric Artificial Synapse

Advanced Materials, EarlyView.
Colonoscopic continuum robots lack sensing, endangering intestinal tissue. An ideal sensing array is hard to integrate. This work introduces a 3D crosslinked stretchable E‐armor with full‐coverage and multiplexing. It has bimodal sensing, forms a triboelectric synapse, uses CNN‐LSTM, and has a hydrogel and innovative triboelectric materials.
Yuyang Sun, Tao Chen, Dongsheng Li, Hanyang Li, Tianci Ji, Fengxia Wang, Lining Sun, Chengkuo Lee, Huicong Liu   +8 more
wiley   +1 more source

Testing Machine Learning Models to Predict Postoperative Ileus after Colorectal Surgery

Current Oncology
Background: Postoperative ileus (POI) is a common complication after colorectal surgery, leading to increased hospital stay and costs. This study aimed to explore patient comorbidities that contribute to the development of POI in the colorectal surgical ...
Garry Brydges, George J. Chang, Tong J. Gan, Tsuyoshi Konishi, Vijaya Gottumukkala, Abhineet Uppal   +5 more
doaj   +1 more source

Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics

Journal of Translational Medicine, 2023
Background Radiosensitivity of rectal cancer is related to the radiotherapy efficacy and prognosis of patients with rectal cancer, and the genes and molecular mechanisms related to radiosensitivity of rectal cancer have not been clarified.
Yi Liu, Yanguang Yang, Feng Ni, Guomei Tai, Cenming Yu, Xiaohui Jiang, Ding Wang   +6 more
doaj   +1 more source