Results 101 to 110 of about 225,683 (335)

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Performance Characteristics of a New Flexible Nitinol 19-Gauge Endoscopic Ultrasound-Guided Fine Needle Aspiration Needle

Gut and Liver, 2013
Solitary rectal ulcer syndrome (SRUS) is a rare, benign disorder in children that usually presents with rectal bleeding, constipation, mucous discharge, prolonged straining, tenesmus, lower abdominal pain, and localized pain in the perineal area.
doaj   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

Advanced Science, EarlyView.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning, Munir H. Buhaya, Victor V. Nguyen, Afeefah Khazi‐Syed, Haider A. Ali, Adil Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, Victor D. Varner, Cheryl M. Lewis, Emina H. Huang, Jacopo Ferruzzi   +18 more
wiley   +1 more source

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

Advanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang, Huanyu Wang, Qianqian Kang, Ruping Pan, Rui He, Min Yang, Jiadai Liu, Xuemin Peng, Yuyu Xie, Hongyan Deng, Wenshe Wang, Zengzhe Zhu, Jing Ge, Yulian Liu, Ronghui Gao, Yaming Guo, Peng Yu, Limeng Pan, Danpei Li, Pema Maretich, Xiaoping Luo, Xuefeng Yu, Yong Chen   +22 more
wiley   +1 more source

Solitary Rectal Ulcer Syndrome - A Rare Entity in the Pediatric Population [PDF]

Türk Patoloji Dergisi
Objective: To study and correlate the clinicopathological findings of Solitary Rectal Ulcer Syndrome (SRUS) in 10 pediatric patients. Material and Methods: This study is a retrospective study of patients from January 2017 to June 2024.
Megha SAWHNEY, Jyotsna MADAN, Devajit NATH, Akanksha BHATIA, Neema TIWARI, Umesh SHUKLA   +5 more
doaj   +1 more source

MR‐DELTAnet: A Longitudinal MRI‐Transformer Model Predicting Pathological Complete Response and Revealing Immune Microenvironment via scRNA‐seq in Locally Advanced Rectal Cancer

Advanced Science, EarlyView.
The MR‐DELTAnet model utilizes longitudinal MRI to predict treatment response after neoadjuvant chemoradiotherapy in locally rectal cancer patients, accurately identifying patients likely to achieve pathological complete response for personalized management.
Wuteng Cao, Huaxian Chen, Jiao Li, Yihui Zheng, Liqing Xie, Guozhong Xiao, Zeyan Wang, Fen Yuan, Junhong Chen, Chongbao Sun, Jing Dai, Jinping Zeng, Xinhua Wang, Lei Wu, Hongcheng Lin   +14 more
wiley   +1 more source

Oral-to-rectum microbial transmission in orthopedic patients without a history of intestinal disorders

Frontiers in Cellular and Infection Microbiology
The enrichment of oral taxa in the gut has recently been reported as a notable alteration in the microbial balance in patients with intestinal disorders. However, translocation in populations without such diseases remains controversial. In this study, we
Ge Lin, Shinya Kageyama, Aiko Maeda, Eiji Sakamoto, Jiale Ma, Mikari Asakawa, Michiko Furuta, Yoshihisa Yamashita, Toru Takeshita   +8 more
doaj   +1 more source

Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy [PDF]

, 2011
Juliana Schwaab, Karoline Horisberger, Philipp Ströbel, Beatrice Bohn, Deniz Gencer, Georg Kähler, Peter Kienle, Stefan Post, Frederik Wenz, Wolf‐Karsten Hofmann, Ralf‐Dieter Hofheinz, Philipp Erben   +11 more
openalex   +1 more source

Inflammatory Rectal Polyp with Osseous Metaplasia: Is It a Distinctive Disease Entity?

, 2021
Cansu Benli Işık, Hatice ÖLGER UZUNER, Mustafa Bakırtaş, Ahmet Saraç   +3 more
openalex   +2 more sources