Results 81 to 90 of about 224,300 (306)

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Rectal and Naris Swabs: Practical and Informative Samples for Analyzing the Microbiota of Critically Ill Patients

mSphere, 2018
Commensal microbiota are immunomodulatory, and their pathological perturbation can affect the risk and outcomes of infectious and inflammatory diseases.
Saumya Bansal, Jenny P. Nguyen, Aleksandra Leligdowicz, Yu Zhang, Kevin C. Kain, Daniel R. Ricciuto, Bryan Coburn   +6 more
doaj   +1 more source

Integrative analysis of the colorectal cancer proteome : potential clinical impact [PDF]

, 2016
Peer ...
Alnabulsi, Abdo, Murray, Graeme I.
core   +2 more sources

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Solitary rectal ulcer syndrome: MRI findings and differentiation from rectal cancer

Insights into Imaging
Background Systematic MRI findings of solitary rectal ulcer syndrome (SRUS) are lacking. We aimed to evaluate the MRI findings of SRUS and to identify the MRI features that differentiate SRUS from rectal cancer.
Peiyi Xie, Xiaoying Lou, Shuai Fu, Xiaohui Di, Qitong Huang, Zhiming Zeng, Kexin Niu, Junying Zhu, Meiyu Hu, Xiaochun Meng   +9 more
doaj   +1 more source

MRI in local staging of rectal cancer: an update

Diagnostic and Interventional Radiology, 2014
Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical ...
Ümit Tapan, Mustafa Özbayrak, Servet Tatlı   +2 more
doaj   +1 more source

216 Jewish Hospital of St. Louis [PDF]

, 1987
https://digitalcommons.wustl.edu/bjc_216/1185/thumbnail ...

core   +1 more source

Management of a Case of Colovesical Fistula with Fecaluria as First Sign [PDF]

, 2015
Introduction. Fecaluria and pneumaturia are the patognomonic signs of an abnormal communication between the bladder and the intestinal tract. Therefore, when a history of digestive signs, symptoms or digestive diseases is missing, this borderline ...
Andresanu, A., Baston, C., Brasoveanu, V., Crasneanu, M., Dick, A., Domnisor, L., Gingu, C., Ianiotescu, I., Martiniuc, A., Sinescu, I.   +9 more
core   +2 more sources

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Surgical Treatment of Rectal Prolapse (History of the Issue and Modern Perspective — Literature Review)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to assess the data on the most common surgical interventions for rectal prolapse.Key points. At present, there are more than 100 methods of surgical correction of rectal prolapse that are carried out by means of the perineal or abdominal approach ...
O. M. Biryukov, A. A. Mudrov, A. Yu. Titov, I. V. Kostarev, A. S. Lukianov, E. E. Zharkov, T. Yu. Shavrina, S. I. Achkasov   +7 more
doaj   +1 more source