Results 81 to 90 of about 2,449,254 (296)

Solitary rectal ulcer syndrome: MRI findings and differentiation from rectal cancer

Insights into Imaging
Background Systematic MRI findings of solitary rectal ulcer syndrome (SRUS) are lacking. We aimed to evaluate the MRI findings of SRUS and to identify the MRI features that differentiate SRUS from rectal cancer.
Peiyi Xie, Xiaoying Lou, Shuai Fu, Xiaohui Di, Qitong Huang, Zhiming Zeng, Kexin Niu, Junying Zhu, Meiyu Hu, Xiaochun Meng   +9 more
doaj   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Surgical Treatment of Rectal Prolapse (History of the Issue and Modern Perspective — Literature Review)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to assess the data on the most common surgical interventions for rectal prolapse.Key points. At present, there are more than 100 methods of surgical correction of rectal prolapse that are carried out by means of the perineal or abdominal approach ...
O. M. Biryukov, A. A. Mudrov, A. Yu. Titov, I. V. Kostarev, A. S. Lukianov, E. E. Zharkov, T. Yu. Shavrina, S. I. Achkasov   +7 more
doaj   +1 more source

Rectal and Naris Swabs: Practical and Informative Samples for Analyzing the Microbiota of Critically Ill Patients

mSphere, 2018
Commensal microbiota are immunomodulatory, and their pathological perturbation can affect the risk and outcomes of infectious and inflammatory diseases.
Saumya Bansal, Jenny P. Nguyen, Aleksandra Leligdowicz, Yu Zhang, Kevin C. Kain, Daniel R. Ricciuto, Bryan Coburn   +6 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Primary Rectal Syphilis Mimicking Lymphoma: A Case Report and Literature Review

Journal of the Korean Society of Radiology
Primary rectal syphilis is a rare disease that can be misdiagnosed as lymphoma or other rectal cancers on sigmoidoscopy or CT. Here, we report a case of primary rectal syphilis mimicking rectal malignancy in a 23-year-old male who presented with a ...
Hyunyoung Bae, Jungheum Cho, Hyuk Jung Kim, Suk Ki Jang, Hee Young Na, Jin Ho Paik   +5 more
doaj   +1 more source

Rectosigmoid Tumor Causing Rectal Prolapse: Case Report

, 2016
Rectal prolapse is believed to develop secondary to anatomical defects. Rectosigmoid tumors are rare causes of this condition. This must be kept in mind in patients with prolapse; colonoscopic examination is recommended and biopsy should be performed ...
Kenan Binnetoğlu, Turgut Anuk, Barlas Sülü, Mahmut Can Yağmurdur, Tülay Diken Allahverdi, Musa Sinan Eren   +5 more
core   +2 more sources

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Case Report: A case of perirectal abscess complicated with rectal necrosis

Frontiers in Surgery
Rectal necrosis represents the extreme progression of ischemic proctitis. Given the unique blood supply of the rectum, which features an extensive collateral circulation, cases of rectal necrosis are extremely rare, accounting for 2%–5% of the ischemic ...
Yingfeng Xu, Zhiting Wang, Jianwen Hu, Jiajia Xie, Shiwei Chen, Ke Ke   +5 more
doaj   +1 more source

Rectal infections with chlamydia and gonorrhoea in women attending a multiethnic sexually transmitted diseases urban clinic

, 2010
Sexually transmitted rectal infections with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC) have been well documented in men who have sex with men (MSM). Few studies have described infections in women who engage in anal intercourse.
M Alcaide, J Castro, T Hunte, Castro, J, Hunte, T, Alcaide, M   +5 more
core   +1 more source