Results 51 to 60 of about 2,449,254 (296)
Research progress on the role of colon rectal neoplasia differentially expressed RNA in diseases [PDF]
, 2022 Colon rectal neoplasia differentially expressed (CRNDE) RNA is a long non-coding RNA molecule that regulates gene expression at multiple levels including transcriptional, post-transcriptional and translational levels, plays a role in a variety of ...
LI Shuang, LI Yang
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Frontiers in ImmunologySecukinumab, a monoclonal antibody targeting interleukin-17A, is effective for treating moderate-to-severe plaque psoriasis but may induce paradoxical inflammatory bowel disease, particularly Crohn’s disease. We describe a 41-year-old male with a history
Huiling Dai +6 more
doaj +1 more source
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Arthritis Care &Research, EarlyView.Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar +5 more
wiley +1 more source
BACTERIOLOGICAL STUDIES OF SALMONELLA Typhimurium ISOLATED FROM COW CALVES AND LAMBS [PDF]
Assiut Veterinary Medical Journal, 2014 Salmonellae are considered one of the most important microorganisms that cause diseases in man and animals. The current research aims to obtain complete picture of Salmonella typhimurium.
LAMYAA, M. REDA, SAHAR R. MOHAMED
doaj +1 more source
Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer
Arthritis Care &Research, EarlyView.Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source
SOME CLINICAL OBSERVATIONS IN RECTAL DISEASES. [PDF]
JAMA: The Journal of the American Medical Association, 1899 There is no surgeon of much experience in rectal surgery but has encountered from time to time cases of PRURITUS ANI that defied all his efforts for relief. I have lately discovered, in several of my cases, a cause for chronic pruritus, which has heretofore escaped my attention, and may possibly not have been observed by others. I therefore speak of it
openaire +2 more sources
Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract
Advanced Robotics Research, EarlyView.We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis +7 more
wiley +1 more source
, 1997 This study investigated the effects of acute hyperglycemia on conscious rectal perception in response to two different rectal distension paradigms. Eleven healthy males were studied in random order on two separate days during euglycemia and hyperglycemia
core +1 more source