Results 91 to 100 of about 2,418,369 (395)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Simple Recurrent Units for Highly Parallelizable Recurrence [PDF]

open access: yesConference on Empirical Methods in Natural Language Processing, 2017
Common recurrent neural architectures scale poorly due to the intrinsic difficulty in parallelizing their state computations. In this work, we propose the Simple Recurrent Unit (SRU), a light recurrent unit that balances model capacity and scalability ...
Tao Lei   +4 more
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Peripheral ossifying fibroma in the maxillary arch

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Many types of localized reactive lesions may occur on the gingiva, including focal fibrous hyperplasia, pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma.
V A Trasad   +3 more
doaj   +1 more source

Can metastasis and recurrence be detected with Endocan and Vascular Endothelial Growth Factor in thyroid papillary cancer?

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2020
Background. Endocan is known to be associated with different type of malignancies and vascular endothelial growth factor (VEGF) has been shown to upregulate endocan expression.
Hande Peynirci   +5 more
doaj   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Recurrence interval analysis of high-frequency financial returns and its application to risk estimation

open access: yes, 2009
We investigate the probability distributions of the recurrence intervals $\tau$ between consecutive 1-min returns above a positive threshold $q>0$ or below a negative threshold ...
Fei Ren   +8 more
core   +1 more source

On Hyper-Generalized Recurrent Finsler Spaces [PDF]

open access: yesarXiv, 2017
The aim of the present paper is to investigate new types of recurrence in Finsler geometry, namely, hyper-generalized recurrence and generalized conharmonic recurrence. The properties of such recurrences and their relations to other Finsler recurrences are studied.
arxiv  

Local Cancer Recurrence: The Realities, Challenges, and Opportunities for New Therapies

open access: yesCa, 2018
Locoregional recurrence negatively impacts both long‐term survival and quality of life for several malignancies. For appropriate‐risk patients with an isolated, resectable, local recurrence, surgery represents the only potentially curative therapy ...
D. Mahvi   +4 more
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

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