Results 91 to 100 of about 1,879,819 (343)

Recurrence and lyapunov exponents

, 2002
We prove two inequalities between the Lyapunov exponents of a diffeomorphism and its local recurrence properties.
Saussol, B., Troubetzkoy, S., Vaienti, S.   +2 more
core   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Predicting recurrence and recurrence-free survival in initially unresectable hepatocellular carcinoma: a novel nomogram for patients undergoing conversion hepatectomy with lenvatinib, PD-1 inhibitor, and interventional therapy

Frontiers in Immunology
PurposeThis research aims to develop prognostic nomograms to predict tumor recurrence and recurrence-free survival (RFS) in individuals with initially unresectable hepatocellular carcinoma (uHCC) who were later subjected to conversion hepatectomy ...
Cheng Xu, Zhihong Tang, Meng Wei, Danxi Liu, Qingqing Pang, Baishan Huang, Xinglin Mo, Feixiang Wu, Feixiang Wu   +8 more
doaj   +1 more source

RECURRENT IMMERSIONS

Demonstratio Mathematica, 1999
A submanifold \(f: M^m \to \mathbb{R}^{m+d}\) is said to have pointwise \(k\)-planar normal section (P\(k\)-PNS) if, for each normal section \(\gamma\), the set \(\{\gamma'(0), \gamma''(0), {\cdots} , \gamma^{(k+1)}(0) \}\) is linearly dependent. Such an \(M\) is called proper (\(\text{PP}k\text{-PNS}\) if it is not P(\(k-1\))-PNS [\textit{B.-Y.
Arslan, Kadri, Deszcz, Ryszard, Murathan, Cengizhan, Özgür, Cihan   +3 more
openaire   +4 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

p-Numerical Semigroups of Triples from the Three-Term Recurrence Relations

Axioms
Many people, including Horadam, have studied the numbers Wn, satisfying the recurrence relation Wn=uWn−1+vWn−2 (n≥2) with W0=0 and W1=1. In this paper, we study the p-numerical semigroups of the triple (Wi,Wi+2,Wi+k) for integers i,k(≥3).
Jiaxin Mu, Takao Komatsu
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Epigenetic Characteristics in Primary and Recurrent Glioblastoma—Influence on the Clinical Course

Biomedicines
Objective: Epigenetic tumor characteristics are in focus for glioblastoma prognosis. This raises the question if these characteristics present with stable expression during the progression of the disease, and if potential temporal instability might ...
Alexander Quiring, Hannah Spielmann, Fritz Teping, Safwan Saffour, Fatemeh Khafaji, Walter Schulz-Schaeffer, Nathan Monfroy, Joachim Oertel, Stefan Linsler, Christoph Sippl   +9 more
doaj   +1 more source

Factors linked to early recurrence of small hepatocellular carcinoma after hepatectomy: Univariate and multivariate analyses [PDF]

, 1991
Ken Shirabe, Takashi Kanematsu, Takashi Matsumata, Eisuke Adachi, K Akazawa, Keizō Sugimachi   +5 more
openalex   +1 more source