Results 121 to 130 of about 1,763,065 (324)
Corrigendum: Xanthomatous Hypophysitis: A Case Report and Comprehensive Literature Review
Jianyu Zhu+12 more
doaj +1 more source
On the Strong Recurrence of Recurrent RWRE
We consider a recurrent RWRE $(X_n)_{n \in \mathbb{N}_0}$ on $\mathbb{Z}$ and investigate the quenched return probabilities of the RWRE to the origin for which we state results on their decay in terms of summability. Additionally, we give some examples for recurrent RWRE with a multidimensional state space which give reason for the part "strong ...
openaire +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
The Present Position of the Radical Abdomino-Perineal Operation for Cancer of the Rectum in Regard to Mortality and Post-Operative Recurrence [PDF]
W. Ernest Miles
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source