Results 121 to 130 of about 1,206,872 (317)

Biochemical properties of collagen metabolism in patients with recurrent genital prolapse [PDF]

open access: yesMedičnì Perspektivi, 2013
Purpose – to determine the features of collagen metabolism state in women with recurrent genital prolapse at the stage of scheduled surgery and in postoperative period using prolene implants.
Banakhevich R.М.
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Effects of perioperative anesthetics on the postoperative prognosis of patients undergoing surgery for cervical cancer

open access: yesFrontiers in Pharmacology
Cervical cancer is a common malignancy among women, and tumor excision is the most common surgical intervention. Anesthetics used during surgery include general intravenous, volatile, local anesthetics, sedative and analgesic. Studies have shown that the
Linyan Deng   +14 more
doaj   +1 more source

Prediction of bladder tumor relapse based on the risk factors and characteristics of the treatment [PDF]

open access: yesMedičnì Perspektivi, 2015
Objectives. To investigate the possibility of predicting recurrence of bladder tumors based on the clinical and morphological features of the disease and preoperative intravesical instillation of probiotic Aerococcus viridans 167.
Molchanov R.N., Blyuss O.B.
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Features of recurrence of varicose disease of the lower limb and its surgical correction

open access: yesАмбулаторная хирургия
Despite the rapid development and rapid spread of minimally invasive techniques in the surgical treatment of chronic venous diseases in recent years, the relapse rate, taking into account the postoperative period, continues to remain high.
P. N. Myshentsev, S. E. Katorkin
doaj   +1 more source

On the Strong Recurrence of Recurrent RWRE

open access: yes, 2012
We consider a recurrent RWRE $(X_n)_{n \in \mathbb{N}_0}$ on $\mathbb{Z}$ and investigate the quenched return probabilities of the RWRE to the origin for which we state results on their decay in terms of summability. Additionally, we give some examples for recurrent RWRE with a multidimensional state space which give reason for the part "strong ...
openaire   +2 more sources

Recurrence-free survival (RFS) was compared between GSN and OAS2 mRNA-overexpressing and–underexpressing tumors in the CIT cohorts (GSE39582, n = 566).

open access: yes, 2018
Recurrence-free survival (RFS) was compared between GSN and OAS2 mRNA-overexpressing and–underexpressing tumors in the CIT cohorts (GSE39582, n = 566).
Yong Sik Yoon (5687843)   +12 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Experts’ views on recurrence and progression of varicose veins

open access: yesАмбулаторная хирургия
Introduction. Despite modern advances in technologies for the treatment and prevention of varicose veins, there is currently no radical treatment for varicose veins.
V. Yu. Bogachev   +5 more
doaj   +1 more source

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