Results 121 to 130 of about 1,361,051 (317)

Recurrence-free survival (RFS) was compared between GSN and OAS2 mRNA-overexpressing and–underexpressing tumors in the CIT cohorts (GSE39582, n = 566).

open access: yes, 2018
Recurrence-free survival (RFS) was compared between GSN and OAS2 mRNA-overexpressing and–underexpressing tumors in the CIT cohorts (GSE39582, n = 566).
Yong Sik Yoon (5687843)   +12 more
core   +1 more source

Matrix interpretation of multiple orthogonality [PDF]

open access: yes, 2010
In this work we give an interpretation of a (s(d + 1) + 1)-term recurrence relation in terms of type II multiple orthogonal polynomials.We rewrite this recurrence relation in matrix form and we obtain a three-term recurrence relation for vector ...
Branquinho, Amílcar   +2 more
core   +1 more source

Oral teicoplanin for successful treatment of severe refractory Clostridium difficile infection

open access: yesJournal of Infection in Developing Countries, 2015
Introduction: Clostridium difficile is the leading cause of hospital-acquired diarrhoea. There is no defined protocol for treating severe Clostridium difficile infection (CDI) refractory to vancomycin or vancomycin and metronidazole combination therapy ...
Natasa Popovic   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Recurrence of a modified random walk and its application to an economic model [PDF]

open access: yes
A modification of Chung and Fuchs’ (Mem. Amer. Math. Soc., 6 (1951), pp. 1-12) recurrence theorem for random walks leads to an analogous result for a different discrete parameter Markov process.
Salant, Stephen W., Wenocur, Roberta S.
core  

A joint frailty model to estimate the recurrence process and the disease-specific mortality process without needing the cause of death.

open access: yes, 2014
In chronic diseases, such as cancer, recurrent events (such as relapses) are commonly observed; these could be interrupted by death. With such data, a joint analysis of recurrence and mortality processes is usually conducted with a frailty parameter ...
Roch Giorgi   +8 more
core   +1 more source

Recurrent phaeochromocytoma

open access: yesInternational Journal of Clinical Practice, 1990
The recurrence of symptoms and hypertension in a patient who has previously undergone an operation for phaeochromocytoma should alert the physician to the need to investigate for recurrent tumour. Failure to perform complete excision of the adrenal gland containing the tumour may lead to disseminated recurrence.
P H, Rowe   +5 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Laparoscopic Transabdominal Preperitoneal Repair of Inguinal Hernia: A Retrospective Study of 1104 Patients [PDF]

open access: yesAl-Anbar Medical Journal
Background: Hernia surgery is one of the most common operations worldwide. Surgery remains the primary treatment for hernias, with limited benefit from conservative management—initially, laparoscopic repair offered better diagnostics, less chronic ...
Mohamed Ghali   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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