Results 61 to 70 of about 175,685 (330)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

FEATURE EXTRACTION OF MOTOR IMAGERY EEG SIGNALS BASED ON MULTI-SCALE RECURRENCE PLOT AND SDA [PDF]

, 2021
Wenbo Wang, Lin Sun, Guici Chen
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

The Application of Recurrence Plots to Identify Nonlinear Responses Using Magnetometer Data for Wind Turbine Design

Machines
This work uses recurrence plots (RPs) to identify nonlinearities and non-stationary conditions in wind turbines. Traditionally, recurrence plots have been applied to vibration or acoustic data; this paper applies them to magnetometer and accelerometer ...
Juan Carlos Jauregui-Correa, Luis Morales-Velazquez   +1 more
doaj   +1 more source

Recurrence Plot Based Measures of Complexity and its Application to Heart Rate Variability Data

, 2002
The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there are several ...
A. Hempelmann, A. L. Goldberger, A. Voss, A. Witt, A. Wolf, Alexander Schirdewan, B. Blasius, C. L. Webber, Jr., E. M. Oblow, H. D. I. Abarbanel, H. V. Huikuri, J. B. Gao, J. B. Gao, J. Kurths, J. Kurths, J. M. Nese, J. O. Diaz, J. P. Zbilut, J.-P. Eckmann, Jürgen Kurths, K. B. Marvel, L. Glass, L. Glass, L. L. Trulla, M. C. Casdagli, N. Wessel, N. Wessel, Niels Wessel, Norbert Marwan, P. E. Rapp, R. Engbert, R. Wackerbauer, S. Guzzetti, U. Schwarz, Udo Meyerfeldt   +34 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Detection of Causal Relations in Time Series Affected by Noise in Tokamaks Using Geodesic Distance on Gaussian Manifolds

Entropy, 2017
: Modern experiments in Magnetic Confinement Nuclear Fusion can produce Gigabytes of data, mainly in form of time series. The acquired signals, composing massive databases, are typically affected by significant levels of noise.
Andrea Murari, Teddy Craciunescu, Emmanuele Peluso, Michela Gelfusa, JET Contributors   +4 more
doaj   +1 more source

Recurrence plot features of ECG signals [PDF]

, 1999
Single beats from ECG recording were used to demonstrate how the nonlinear dynamical analysis method of recurrence plots can be used to qualitatively describe data.
Mewett, David, Nazeran, Homer, Reynolds, Karen Jane   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Detection of Spatio-Temporal Recurrent Patterns in Dynamical Systems

Frontiers in Applied Mathematics and Statistics, 2019
Background: The study of repetitive (quasi-periodic) spatio-temporal patterns in complex dynamical systems with a well defined spatial structure may be complicated if the recurrent behavior is confined to specific local regions, where it lasts for a ...
Pietro Bonizzi, Ralf Peeters, Stef Zeemering, Arne van Hunnik, Olivier Meste, Joël Karel   +5 more
doaj   +1 more source