Results 71 to 80 of about 3,760,531 (362)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Generalized Dyck paths of bounded height [PDF]

, 2013
Generalized Dyck paths (or discrete excursions) are one-dimensional paths that take their steps in a given finite set S, start and end at height 0, and remain at a non-negative height.
Bacher, Axel
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

On a recurrence relation

, 2014
In this paper, we investigate the nature of the solutions to the following difference equation: where the initial values , parameters α, β, B, C are positive and k ∈ {1,2,3,…} is fixed. We study the boundedness nature and global behavior of its solutions.
Reza Mostafaei, Narges Rastegar
semanticscholar   +1 more source

Restart uncertainty relation for monitored quantum dynamics [PDF]

Proceedings of the National Academy of Sciences of the United States of America
Significance A time-energy uncertainty relation is proposed, connecting the fluctuating quantum recurrence time to the energies of the quantum system. This relation reveals a broadening of transitions in the mean quantum recurrence time, which is defined
Ruoyu Yin, Qingyuan Wang, Sabine Tornow, Eli Barkai   +3 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Number of spanning trees of some families of graphs generated by a triangle

Journal of Taibah University for Science, 2019
In mathematics, one always tries to get new structures from given ones. This also applies to the realm of graphs, where one can generate many new graphs from a given set of graphs.
S. N. Daoud
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Binomial sums about Bernoulli, Euler and Hermite polynomials [PDF]

Discrete Mathematics Letters, 2020
Xiaoyuan Wang, Wenchang Chu
doaj   +1 more source