Results 101 to 110 of about 347,214 (307)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Mass selection in maize composites by means of selection indices

, 1972
General considerationsA selection index may be applied to selection based either upon the performance of single plants or upon the performance of progenies.
Wolff, F., de
core  

Recurrent haploid selection in a population of sweet corn (Zea mays convar. saccharata)

, 2022
Recurrent haploid selection is based on the phenotype of haploid plants. This selection method was reported to be very effective because of the high selection pressure.
Aichholz, Charlotte, Becker, Heiko C.; 3 Department of Crop Sciences, Division of Plant Breeding Methodology Georg‐August‐Universität Göttingen Göttingen Germany, Horneburg, Bernd, Becker, Heiko C., Horneburg, Bernd; 2 Section of Genetic Resources and Organic Plant Breeding Georg‐August‐Universität Göttingen Göttingen Germany   +4 more
core   +1 more source

Realized genomic selection across generations in a reciprocal recurrent selection breeding program of Eucalyptus hybrids. [PDF]

Front Plant Sci, 2023
Simiqueli GF, Resende RT, Takahashi EK, de Sousa JE, Grattapaglia D.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Population improvement via recurrent selection drives genetic gain in upland rice breeding. [PDF]

Heredity (Edinb), 2023
Pereira de Castro A, Breseghello F, Furtini IV, Utumi MM, Pereira JA, Cao TV, Bartholomé J.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss [PDF]

, 2012
Decidualization renders the endometrium transiently receptive to an implanting blastocyst although the underlying mechanisms remain incompletely understood.
Nicou, M, Zoe Webster, Emma S. Lucas (109222), Sean James, Keisuke Murakami, Mulac-Jericevic, B, Murakami Keisuke, Yazan Abdallah, Jaya Nautiyal (109208), Sandra Šućurović (109212), Salker Madhuri S., Abdallah, Y, Nautiyal, Jaya, Marilena Nicou, Jan J Brosens, Biserka Mulac-Jericevic (54989), Lucas Emma S., Jennifer H Steel, Mulac-Jericevic Biserka, Marilena Nicou (109216), Webster Zoe, Brosens, J J, James Sean, Croy, B. A. (B. Anne), Nautiyal Jaya, Lucas, E S, Siobhan Quenby, Yogesh Singh (109219), Yogesh Singh, Madhuri S. Salker (109206), Nicou, Marilena, Imperial College London, Quenby, Siobhan, Singh, Y, James, S, Nicou Marilena, Abdallah Yazan, Webster, Zoe, Croy, B A, Quenby Siobhan, Yazan Abdallah (109236), Brosens, Jan J., Christian Mark, Mark Christian (22637), Šućurović, Sandra, Madhuri S Salker, Croy B. Anne, Mark Christian, Steel Jennifer H., Singh Yogesh, Christian, M, Keisuke Murakami (109225), Warwick, Siobhan Quenby (109244), Biserka Mulac-Jericevic, Jan J. Brosens (109247), Lucas, Emma S., Queens University Canada, Singh, Yogesh, Dr., B. Anne Croy (109241), Rijeka, Šućurović Sandra, Jaya Nautiyal, Yi-Wah Chan, B Anne Croy, Murakami, K, Chan, Yi-Wah, James, Sean G., Brosens Jan J., Zoe Webster (109211), Sandra Sućurović, Murakami, Keisuke, Steel, Jennifer H., Nautiyal, J, Chan Yi-Wah, Quenby, S, Webster, Z, Salker, Madhuri S., Sean James (109232), Steel, J H, Sucurovic, S, Yi-Wah Chan (109228), Christian, Mark, Mulac-Jericevic, Biserka, Abdallah, Yazan, Chan, Y W, Emma S Lucas, Salker, M S, Jennifer H. Steel (109209)   +88 more
core   +1 more source

Simulation of marker-assisted recurrent selection in autogamous species

Crop Breeding and Applied Biotechnology, 2002
This work used computer simulation to evaluate marker-assisted selection (MAS) in recurrent selection of autogamous species. Base populations were simulated by crossing each of five inbred lines with two others.
Eduardo Bearzoti, Roland Vencovsky
doaj  

Use of marker-assisted selection in creation of models of cereal crops varieties resisted to abiotic stresses

Аграрная наука Евро-Северо-Востока, 2018
Under the conditions of constantly changing industry demands and worsening of ecological situation, models of agricultural crops varieties must be regularly modernized.
E. M. Lisitsyn
doaj   +1 more source