Results 121 to 130 of about 2,675,582 (207)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Selection aiming at upright growth habit common bean with carioca type grains

open access: yesCrop Breeding and Applied Biotechnology, 2005
Aiming at common bean lines with a high grain yield, upright growth habit and carioca type grains, ten common bean lines were crossed in a diallel scheme. The resulting populations were evaluated as to their capacity of generating superior lines.
Welcimar Gonçalves da Cunha   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

DESIGN-ADAPTIVE POINTWISE NONPARAMETRIC REGRESSION ESTIMATION FOR RECURRENT MARKOV TIME SERIES [PDF]

open access: yes
A general framework is proposed for (auto)regression nonparametric estimation of recurrent time series in a class of Hilbert Markov processes with a Lipschitz conditional mean.
Guerre
core  

Means and variances of some characters in base populations, with emphasis on grain yield in soybean

open access: yesCrop Breeding and Applied Biotechnology, 2002
The aim of this study was to evaluate in early generations of self-fertilization the potential of single, double and multiple crosses, as producers of base population for soybean breeding programs. The crosses.
Henrique Stoco Bizeti   +2 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Genetic gain for grain yield and popping expansion in full-sib recurrent selection in popcorn

open access: yesCrop Breeding and Applied Biotechnology, 2002
A first cycle of full-sib recurrent selection was conducted in a popcorn base population, with the objective of improving popping expansion and grain yield as recommended in a previous study by Pereira and Amaral Júnior (2001).
Máskio Daros   +2 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Heritability estimated from recurrent selection experiments in maize [PDF]

open access: yes, 1987
Estimates of heritability allow breeders to calculate expected progress from selection relative to germplasm sources, the type of breeding procedure used to improve the germplasm, and the amount of testing of genetic material. The objective of this study
Lamkey, Kendall, Hallauer, A. R.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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