Results 81 to 90 of about 781,216 (295)

Performance of improved sunflower populations for resistance to Alternaria leaf blight and productivity [PDF]

Electronic Journal of Plant Breeding, 2011
An experiment was conducted to evaluate the performance of two sunflower populations viz., C3 (three cycles of improvement through recurrent selection without pollen selection) and C3G3 (three cycles of improvement through recurrent selection with pollen
Laxmi C. Patil and R L Ravikumar
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Evaluation of sorghum grain quality for QTL analysis and Marker Assisted Recurrent Selection (MARS) : [P1121] [PDF]

, 2014
Sorghum breeding in Mali mostly focuses on varieties for human consumption. Even if most of breeding efforts concentrate on productivity and adaptation, grain quality is a very important aspect to consider for improved material to be adopted and ...
Davrieux, Fabrice, Fliedel, Geneviève, Guindo, Diarah, Guitton, Baptiste, Kapitan Gnimdu, André, Rami, Jean-François, Teme, Niaba, Vaksmann, Michel   +7 more
core  

Recurrence threshold selection for obtaining robust recurrence characteristics in different embedding dimensions

Chaos: An Interdisciplinary Journal of Nonlinear Science, 2018
The appropriate selection of recurrence thresholds is a key problem in applications of recurrence quantification analysis and related methods across disciplines. Here, we discuss the distribution of pairwise distances between state vectors in the studied system’s state space reconstructed by means of time-delay embedding as the key characteristic that ...
K. Hauke Kraemer, Reik V. Donner, Jobst Heitzig, Norbert Marwan   +3 more
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Use of marker-assisted selection in creation of models of cereal crops varieties resisted to abiotic stresses

Аграрная наука Евро-Северо-Востока, 2018
Under the conditions of constantly changing industry demands and worsening of ecological situation, models of agricultural crops varieties must be regularly modernized.
E. M. Lisitsyn
doaj   +1 more source

Learning Multi-Level Information for Dialogue Response Selection by Highway Recurrent Transformer [PDF]

, 1929
With the increasing research interest in dialogue response generation, there is an emerging branch formulating this task as selecting next sentences, where given the partial dialogue contexts, the goal is to determine the most probable next sentence ...
Chiang, Ting-Rui, Huang, Chao-Wei, Su, Shang-Yu, Chen, Yun-Nung   +3 more
core   +8 more sources