Results 71 to 80 of about 8,773,435 (248)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Use of an Active Canopy Sensor Mounted on an Unmanned Aerial Vehicle to Monitor the Growth and Nitrogen Status of Winter Wheat

Remote Sensing, 2020
Using remote sensing to rapidly acquire large-area crop growth information (e.g., shoot biomass, nitrogen status) is an urgent demand for modern crop production; unmanned aerial vehicle (UAV) acts as an effective monitoring platform.
Jie Jiang, Zeyu Zhang, Qiang Cao, Yan Liang, Brian Krienke, Yongchao Tian, Yan Zhu, Weixing Cao, Xiaojun Liu   +8 more
doaj   +1 more source

Dynamic weight parameter for the Random Early Detection (RED) in TCP networks [PDF]

, 2012
This paper presents the Weighted Random Early Detection (WTRED) strategy for congestion handling in TCP networks. WTRED provides an adjustable weight parameter to increase the sensitivity of the average queue size in RED gateways to the changes in the ...
Murray, D., Hamadneh, N., Dixon, M., Cole, P.   +3 more
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Estimating Corn Growth Parameters by Integrating Optical and Synthetic Aperture Radar Features into the Water Cloud Model

Agriculture
Crop growth parameters are the basis for evaluation of crop growth status and crop yield. The aim of this study was to develop a more accurate estimation model for corn growth parameters combined with multispectral vegetation indexes (VIopt) and the ...
Yanyan Wang, Zhaocong Wu, Shanjun Luo, Xinyan Liu, Shuaibing Liu, Xinxin Huang   +5 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Vegetation Indices as Rapid, Non‐Destructive Tool to Assess Nitrogen Status in Irrigated Rice

Modern Agriculture
The use of optical radiation sensors is a promising strategy for nitrogen management as it reduces the costs of chemical analyses and allows quick decision‐making in the supplementary application of N to irrigated rice.
Marcos Paulo dos Santos, Nívea Patrícia Ribeiro Reges, Alberto Baêta dos Santos, Luís Fernando Stone, Alexandre Bryan Heinemann   +4 more
doaj   +1 more source

QSRED, an algorithm to solve the mismatch between the microscopic and macroscopic behavior of RED gateways [PDF]

, 2010
Network congestion is a phenomenon caused by the extreme demand of restricted network resources. Various congestion control strategies have been proposed to increase network performance.
Murray, D., Michael Dixon, Hamadneh, N., Peter Cole, Dixon, M., Cole, P., Nabhan Hamadneh, David Murray   +7 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source