Results 71 to 80 of about 21,414,113 (306)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Compartiendo aprendizajes, el Proyecto RED SICTA, Parte II

open access: yes, 2010
Locutores: Susana Fevrier y Luis Diego Solórzano Entrevistados: Armando Ferrufino, Diana Savedra, Antonio Silva, Ángela Velázquez.Hoy productores de diversas partes de Centroamérica hablarán del Proyecto de Innovación Agrícola (RED SICTA) y sobre su ...
Instituto Interamericano de Cooperación para la Agricultura (IICA)   +6 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Nicaragua?s Red de Protección Social: An Exemplary but Short-Lived Conditional Cash Transfer Programme [PDF]

open access: yes
This country study investigates the history and eventual conclusion of Nicaragua?s conditional cash transfer programme, the Red de Protección Social (RPS).
Charity Moore
core  

Predicting general mental health and exhaustion: the role of emotion and cognition components of personal and collective work-identity

open access: yesHeliyon, 2018
The aim of this study was to investigate relationships between emotion and cognition components of personal and collective work-identity and self-reported general mental health and exhaustion, in Swedish teachers (N = 768).
Ola Nordhall   +2 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Abundance and distribution of delphinids in the Red Sea (Egypt)

open access: yes, 2015
Knowledge about cetaceans in the Red Sea is limited with only a handful of sporadic or spatially-limited studies carried out to date. Funded by the Italian Cooperation through a Debt-for-Nature Swap programme and carried out in collaboration with the ...
Costa, Marina
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Temporal changes in the Red Sea circulation and associated water masses

open access: yes, 2013
Long-term variability of the Red Sea deep water (RSDW) properties was investigated using hydrographic data stretching back to the beginning of the 19th century.
Alraddadi, Turki Metabe
core  

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