Results 41 to 50 of about 233,459 (268)

THE SPRING VARIATION IN TWO DIMENSIONAL MODELING OF RED BLOOD CELL DEFORMABILITY BASED ON GRANULAR

open access: yesSpektra: Jurnal Fisika dan Aplikasinya, 2019
The red blood cell membrane has a complex structure and high deformability. Simulation of that complex red blood cell membrane can simpler use granular-based modeling. Red blood cell is modeled consisting of 50 granular particles connected by springs. An
Ismi Yasifa, Sparisoma Viridi
doaj   +1 more source

Changes in Hematological and Hemorheological Parameters Following Mild COVID-19: A 4-Month Follow-Up Study

open access: yesHematology Reports, 2023
Background: Coronavirus Disease 2019 (COVID-19) was described to affect red blood cells (RBC) in both severe and mild disease courses. The aim of this study was to investigate whether hematological and hemorheological changes that were previously ...
Janina Bros   +7 more
doaj   +1 more source

In vitro study of the fragility and deformability of the sickle cell: the effects of NSAIDs and primaquine [PDF]

open access: yesThe Medical Journal of Basrah University, 2013
Background: The sickle red blood cell differs physiologically from the normal red cell, especially in fragility and viscocity. The effects whether useful or deleterious of various drugs such as antibiotics or analgesics on the sickle red blood cell are ...
Kamla A. Hussein, Nabeel A.J.Ali
doaj   +1 more source

Red blood cell vesiculation in hereditary hemolytic anemia

open access: yesFrontiers in Physiology, 2013
Hereditary hemolytic anemia encompasses a heterogeneous group of anemias characterised by decreased red blood cell survival because of inherited membrane, enzyme, or hemoglobin disorders.
Amr eAlaarg   +4 more
doaj   +1 more source

Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

open access: yesHaematologica, 2020
Hereditary spherocytosis (HS) originates from defective anchoring of the cytoskeletal network to the transmembrane protein complexes of the red blood cell (RBC).
Rick Huisjes   +15 more
doaj   +1 more source

Decreased hematocrit-to-viscosity ratio and increased lactate dehydrogenase level in patients with sickle cell anemia and recurrent leg ulcers. [PDF]

open access: yesPLoS ONE, 2013
Leg ulcer is a disabling complication in patients with sickle cell anemia (SCA) but the exact pathophysiological mechanisms are unknown. The aim of this study was to identify the hematological and hemorheological alterations associated with recurrent leg
Philippe Connes   +11 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Changes in Blood Cell Deformability in Chorea-Acanthocytosis and Effects of Treatment With Dasatinib or Lithium

open access: yesFrontiers in Physiology, 2022
Misshaped red blood cells (RBCs), characterized by thorn-like protrusions known as acanthocytes, are a key diagnostic feature in Chorea-Acanthocytosis (ChAc), a rare neurodegenerative disorder.
Felix Reichel   +20 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Assessment of red blood cell deformability in type 2 diabetes mellitus and diabetic retinopathy by dual optical tweezers stretching technique

open access: yesScientific Reports, 2016
A pilot cross sectional study was conducted to investigate the role of red blood cells (RBC) deformability in type 2 diabetes mellitus (T2DM) without and with diabetic retinopathy (DR) using a dual optical tweezers stretching technique.
Rupesh V Agrawal   +8 more
semanticscholar   +1 more source

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