Results 31 to 40 of about 11,819 (278)

In vitro study of the fragility and deformability of the sickle cell: the effects of NSAIDs and primaquine [PDF]

The Medical Journal of Basrah University, 2013
Background: The sickle red blood cell differs physiologically from the normal red cell, especially in fragility and viscocity. The effects whether useful or deleterious of various drugs such as antibiotics or analgesics on the sickle red blood cell are ...
Kamla A. Hussein, Nabeel A.J.Ali
doaj   +1 more source

Separation of blood cells with differing deformability using deterministic lateral displacement

, 2014
Determining cell mechanical properties is increasingly recognized as a marker-free way to characterize and separate biological cells. This emerging realization has led to the development of a plethora of appropriate measurement techniques. Here, we use a
Nuria Vergara-Irigaray, Whyte, G, Ekpenyong, Andrew, Guck, Jochen, Guck, J, Andrew Ekpenyong, David Holmes, Bailey, Joe, Duke, T, Ekpenyong, A., Bailey, J, Jochen Guck, Vergara-Irigaray, N, Guck, J., Duke, T., Joe Bailey, Vergara-Irigaray, Nuria, Tom Duke, Holmes, D., Holmes, David, Vergara-Irigaray, N., Duke, Tom, Whyte, G., Graeme Whyte, Whyte, Graeme, Holmes, D, Bailey, J., Ekpenyong, A   +27 more
core   +1 more source

Computational identification of phospho-tyrosine sub-networks related to acanthocyte generation in neuroacanthocytosis [PDF]

, 2012
Acanthocytes, abnormal thorny red blood cells (RBC), are one of the biological hallmarks of neuroacanthocytosis syndromes (NA), a group of rare hereditary neurodegenerative disorders.
Pantaleo, Antonella, Angela Siciliano, Jung, Hans H., Pantaleo A., Ruth H. Walker (184548), Dotti Maria Teresa, Bader B., Sara Mazzucco, Lucia De Franceschi (184533), Dotti, Maria Teresa, Tomelleri Carlo, Bader, B, Hans H. Jung (184555), Walker R. H., Mazzucco, Sara, Walker, R H, Scardoni, G, Danek, A, Carlo Tomelleri, Giovanni Scardoni, Sara Mazzucco (184565), Scardoni G, Bader Benedikt, Dotti, M T, Siciliano, Angela, Danek, Adrian, Tomelleri C, Lucia De Franceschi, Giovanni Scardoni (184538), Adrian Danek, Antonella Pantaleo (184574), Pantaleo, A, Pantaleo Antonella, Laudanna Carlo, Jung H. H., Benedikt Bader, Adrian Danek (4947), De Franceschi Lucia, Scardoni G., Siciliano A, Antonella Pantaleo, Danek Adrian, Tomelleri, Carlo, Hans H Jung, Jung, H H, Carlo Laudanna (184575), Laudanna C., Benedikt Bader (184560), Jung Hans H., DOTTI, MARIA, De Franceschi L, Jung HH, Tomelleri, C, Walker RH, De Franceschi, L, Pantaleo A, Laudanna, Carlo, Danek A, Carlo Laudanna, Siciliano, A, De Franceschi, Lucia, Maria Teresa Dotti (184569), Walker Ruth H., Scardoni, Giovanni, Ruth H Walker, Maria Teresa Dotti, Mazzucco Sara, Bader B, Scardoni Giovanni, Mazzucco, S, Dotti M. T., Laudanna, C, Angela Siciliano (184571), Siciliano Angela, Carlo Tomelleri (184542), Walker, Ruth H., Bader, Benedikt, Mazzucco S, Danek A.   +78 more
core   +1 more source

Red blood cell vesiculation in hereditary hemolytic anemia

Frontiers in Physiology, 2013
Hereditary hemolytic anemia encompasses a heterogeneous group of anemias characterised by decreased red blood cell survival because of inherited membrane, enzyme, or hemoglobin disorders.
Amr eAlaarg, Raymond eSchiffelers, Raymond eSchiffelers, Wouter W. van Solinge, Richard eVan Wijk   +4 more
doaj   +1 more source

Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

Haematologica, 2020
Hereditary spherocytosis (HS) originates from defective anchoring of the cytoskeletal network to the transmembrane protein complexes of the red blood cell (RBC).
Rick Huisjes, Asya Makhro, Esther Llaudet-Planas, Laura Hertz, Polina Petkova-Kirova, Liesbeth P. Verhagen, Silvia Pignatelli, Minke A.E. Rab, Raymond M. Schiffelers, Elena Seiler, Wouter W. van Solinge, Joan-LLuis Vives Corrons, Lars Kaestner, Maria Mañú-Pereira, Anna Bogdanova, Richard van Wijk   +15 more
doaj   +1 more source

Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease

, 2012
A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid, Wolters, Dirk, Heiß, Christian, Rodriguez Mateos, Ana, Krenz, Thomas, Kuhnle, G. G. C., Cortese-Krott, Miriam M, Rodriguez-Mateos, Ana, Kelm, Malte, Cortese-Knott, Miriam M., Feelisch, Martin, Rodriguez-Mateos, Z, Kroncke, K.-D., Kröncke, Klaus-Dietrich, Sansone, R., Kuhnle, Gunter G. C., Kelm, M., Heiss, C., Krisp, C., Sansone, Roberto, Horn, P., Feelisch, M., Horn, Patrick, Krisp, Christoph, Krenz, T., Hogg, N., Kuhnle, Gunter, Kuhnle, Gunter G.C., Thasian-Sivarajah, S., Thasian-Sivarajah, Sivatharsini, Wolters, D., Cortese-Krott, Miriam M., Hogg, Neil, Cortese-Krott, M. M.   +33 more
core   +1 more source

Decreased hematocrit-to-viscosity ratio and increased lactate dehydrogenase level in patients with sickle cell anemia and recurrent leg ulcers. [PDF]

PLoS ONE, 2013
Leg ulcer is a disabling complication in patients with sickle cell anemia (SCA) but the exact pathophysiological mechanisms are unknown. The aim of this study was to identify the hematological and hemorheological alterations associated with recurrent leg
Philippe Connes, Yann Lamarre, Marie-Dominique Hardy-Dessources, Nathalie Lemonne, Xavier Waltz, Danièle Mougenel, Martin Mukisi-Mukaza, Marie-Laure Lalanne-Mistrih, Vanessa Tarer, Benoit Tressières, Maryse Etienne-Julan, Marc Romana   +11 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Changes in Blood Cell Deformability in Chorea-Acanthocytosis and Effects of Treatment With Dasatinib or Lithium

Frontiers in Physiology, 2022
Misshaped red blood cells (RBCs), characterized by thorn-like protrusions known as acanthocytes, are a key diagnostic feature in Chorea-Acanthocytosis (ChAc), a rare neurodegenerative disorder.
Felix Reichel, Felix Reichel, Martin Kräter, Martin Kräter, Kevin Peikert, Kevin Peikert, Hannes Glaß, Philipp Rosendahl, Maik Herbig, Maik Herbig, Alejandro Rivera Prieto, Alexander Kihm, Giel Bosman, Lars Kaestner, Lars Kaestner, Andreas Hermann, Andreas Hermann, Andreas Hermann, Andreas Hermann, Jochen Guck, Jochen Guck   +20 more
doaj   +1 more source

Red Blood Cell Deformability Index in Diabetic Retinopathy

Hormone and Metabolic Research, 1987
In order to investigate the relationship between haemorheological disturbances and diabetic microangiopathy we have studied the red blood cell deformability index (RBCD-index) by means of a filtration technique in 69 diabetics, aged 49-83 years, and in 40 non diabetic healthy controls (group A) of respective age and sex.
DIAMANTOPOULOS, EJ, RAPTIS, SA, MOULOPOULOS, SD   +2 more
openaire   +3 more sources