Simple Assessment of Red Blood Cell Deformability Using Blood Pressure in Capillary Channels for Effective Detection of Subpopulations in Red Blood Cells. [PDF]
ACS Omega, 2022 Assessment of red blood cell (RBC) deformability as a biomarker requires expensive equipment to induce and monitor deformation. In this study, we present a simple method for quantifying RBC deformability.
Kang YJ +4 more
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Deformability of Stored Red Blood Cells [PDF]
Frontiers in Physiology, 2021 Red blood cells (RBCs) deformability refers to the cells’ ability to adapt their shape to the dynamically changing flow conditions so as to minimize their resistance to flow.
Gregory Barshtein +2 more
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The influence of red blood cell deformability on hematocrit profiles and platelet margination. [PDF]
PLoS Comput Biol, 2020 The influence of red blood cell (RBC) deformability in whole blood on platelet margination is investigated using confocal microscopy measurements of flowing human blood and cell resolved blood flow simulations.
Czaja B +5 more
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Data for assessing red blood cell deformability from microscopy images using deep learning [PDF]
Data in Brief, 2023 Red blood cell (RBC) deformability is a vital biophysical property that dictates the ability of these cells to repeatedly squeeze through small capillaries in the microvasculature.
Erik S. Lamoureux +5 more
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Impact of surface-area-to-volume ratio, internal viscosity and membrane viscoelasticity on red blood cell deformability measured in isotonic condition. [PDF]
Sci Rep, 2019 Osmotic gradient ektacytometry is the gold standard to assess red blood cell (RBC) deformability. It has been proposed that, when measured in isotonic condition, RBC deformability at low shear stress would depend on membrane elasticity while it would be ...
Renoux C +6 more
europepmc +2 more sources
On the Effects of Reactive Oxygen Species and Nitric Oxide on Red Blood Cell Deformability. [PDF]
Front Physiol, 2018 The main function of red blood cells (RBCs) is the transport of respiratory gases along the vascular tree. To fulfill their task, RBCs are able to elastically deform in response to mechanical forces and, pass through the narrow vessels of the ...
Diederich L +12 more
europepmc +2 more sources
Measuring Asymmetric Ionic Current Waveform Through Micropores for Detecting Reduced Red Blood Cell Deformability Due to Plasmodium falciparum Infection [PDF]
SensorsThe mechanisms underlying reduced deformability of red blood cells (RBCs) in Plasmodium falciparum remain unclear. The decrease in RBC deformability associated with malarial infection was measured using ektacytometry, and only mean values were evaluated.
Kazumichi Yokota +3 more
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Red blood cell deformability is diminished in patients with Chronic Fatigue Syndrome. [PDF]
Clin Hemorheol Microcirc, 2019 BACKGROUND: Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a poorly understood disease. Amongst others symptoms, the disease is associated with profound fatigue, cognitive dysfunction, sleep abnormalities, and other symptoms that are made
Saha AK +8 more
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GBT440 improves red blood cell deformability and reduces viscosity of sickle cell blood under deoxygenated conditions. [PDF]
Clin Hemorheol Microcirc, 2018 BACKGROUND: In sickle cell disease (SCD), polymerization of hemoglobin S (HbS) leads to the formation of rigid, non-deformable sickled RBCs. Loss of RBC deformability, sickling and irreversible membrane damage causes abnormal blood rheology, and ...
Dufu K +3 more
europepmc +2 more sources
International Journal of Molecular SciencesThe deformability of red blood cells (RBCs), expressing their ability to change their shape as a function of flow-induced shear stress, allows them to optimize oxygen delivery to the tissues and minimize their resistance to flow, especially in ...
Gregory Barshtein +2 more
exaly +2 more sources