Results 101 to 110 of about 2,320,639 (311)

Performance of extraction methods for extracellular DNA from sediments across marine habitats

open access: yesEnvironmental DNA, 2020
Background Using environmental DNA (eDNA) to detect taxa is quickly becoming an important technique to determine the distribution and diversity of macroorganisms.
Nathan R. Geraldi   +3 more
doaj   +1 more source

From the sea bottom to the red planet with laser-induced breakdown spectroscopy [PDF]

open access: yes, 2016
Laser-induced breakdown spectroscopy (LIBS) constitutes one of the most active research fields in analytical science. Among several important features, ability for adaptation to radically different scenarios constitutes its most valuable asset.
Laserna-Vázquez, José Javier
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Near complete local extinction of iconic anemonefish and their anemone hosts following a heat stress event

open access: yesnpj Biodiversity
A fundamental question in modern-day ecology is: How will populations and their interactions respond to a rapidly changing climate? Documenting local collapses of ecologically and economically important populations can offer insight into broader patterns
Morgan F. Bennett-Smith   +11 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Properties of Red Sea coastal currents [PDF]

open access: yes, 2014
© The Author(s), 2014. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Continental Shelf Research 78 (2014): 51–61, doi:10.1016/j.csr.2014.01.025.Properties of coastal flows
Abualnaja, Yasser   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

A netnography study on branded customer experience: Evidence from the red sea [PDF]

open access: yes, 2009
This study addresses the question of what are the underlying dimensions and messages to self and others that constitute the construct of customer experience.
Ismail, AR, Lim, L, Melewar, TC
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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