Results 101 to 110 of about 2,353,407 (330)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Symmetric Responses to Diet by Plumage Carotenoids in Violet-Sensitive Piciform–Coraciiform Birds

open access: yesDiversity
Biological studies on symmetry can be expanded to consider red (longer wavelengths) and blue (shorter wavelengths) shifts as antisymmetries (opposite-pattern symmetries), which may arise from similar underlying causes (invariant process symmetries).
Robert Bleiweiss
doaj   +1 more source

Frequency Shifts of Spectral Lines Generated by Young's Pinhole Wave Scattering Upon a Quasi-Homogeneous Medium

open access: yesIEEE Photonics Journal, 2017
Frequency shifts of light scattered from either a deterministic or random medium have shown great importance in remote sensing imaging applications, however, such scattering system which combines random scatterer with obstacles has not been specifically ...
Jia Li, Yuechun Shi
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Experimental Characterization of In Silico Red-Shift-Predicted iLOVL470T/Q489K and iLOVV392K/F410V/A426S Mutants. [PDF]

open access: yesACS Omega, 2022
Wehler P   +5 more
europepmc   +1 more source

Extreme Raman red shift: ultrafast multimode non-linear space-time dynamics, pulse compression, and broadly tunable frequency conversion [PDF]

open access: green, 2020
Paolo Carpeggiani   +13 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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