Results 71 to 80 of about 1,913,213 (331)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Triazine herbicide reduced the toxicity of the harmful dinoflagellate Karenia mikimotoi by impairing its photosynthetic systems

Ecotoxicology and Environmental Safety
Triazine herbicides are common contaminants in coastal waters, and they are recognized as inhibitors of photosystem II, causing significant hinderance to the growth and reproduction of phytoplankton.
Xiang-Wu Chen, Heng Chen, Hai-Ling Zhao, Da-Wei Li, Lin-Jian Ou   +4 more
doaj   +1 more source

Growth rates and nitrate uptake of co-occurring red-tide dinoflagellates Alexandrium affine and A. fraterculus as a function of nitrate concentration under light-dark and continuous light conditions

ALGAE, 2019
Copyright © 2019 The Korean Society of Phycology 237 http://e-algae.org pISSN: 1226-2617 eISSN: 2093-0860 Growth rates and nitrate uptake of co-occurring red-tide dinoflagellates Alexandrium affine and A.
Kyung Ha Lee, H. Jeong, Hee Chang Kang, Jin Hee Ok, Ji Hyun You, Sang Ah Park   +5 more
semanticscholar   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Effects of tidal-forcing variations on tidal properties along a narrow convergent estuary [PDF]

, 2018
A 1D analytical framework is implemented in a narrow convergent estuary that is 78 km in length (the Guadiana, Southern Iberia) to evaluate the tidal dynamics along the channel, including the effects of neap-spring amplitude variations at the mouth.
AJF Hoitink, AS Chernetsky, CT Friedrichs, CT Friedrichs, D Prandle, D Prandle, D Prandle, DA Jay, DA Jay, DA Jay, DA Jay, DA Jay, DL Codiga, E Flinchem, E Garel, E Garel, E Garel, E Garel, EF Zhang, Erwan Garel, GB Pillsbury, HHG Savenije, HM Schuttelaars, Huayang Cai, Huayang Cai, Huayang Cai, JC Winterwerp, JJ Dronkers, JM Lincoln, JN Hunt, KR Dyer, L Guo, LC Rijn Van, LS Quaresma, M. Díez-Minguito, MA Teodosio, MG Sassi, MJ Park, R. Familkhalili, S Lanzoni, SR Shetye, ZB Wang   +41 more
core   +1 more source

The Coastal Ocean Circulation Influence on the 2018 West Florida Shelf K .  brevis Red Tide Bloom

Journal of Geophysical Research: Oceans, 2019
Blooms of the harmful alga, Karenia brevis on the west Florida continental shelf are thought to initiate offshore before manifesting as a nuisance along the coastline.
R. Weisberg, Yonggang Liu, C. Lembke, Chuanmin Hu, Katherine A Hubbard, M. Garrett   +5 more
semanticscholar   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Thermal Tides in Fluid Extrasolar Planets

, 2009
Asynchronous rotation and orbital eccentricity lead to time-dependent irradiation of the close-in gas giant exoplanets -- the hot Jupiters. This time-dependent surface heating gives rise to fluid motions which propagate throughout the planet.
Aristotle Socrates, Arras, Batygin, Bodenheimer, Burrows, Cowling, Dobbs-Dixon, Fabrycky, Fortney, Goodman, Lynden-Bell, Newcomb, Phil Arras, Showman, Unno, Winn, Zahn, Zahn   +17 more
core   +1 more source

Variability of Internally Generated Turbulence in an Estuary, from 100 Days of Continuous Observations [PDF]

, 2009
We present detailed observations of internally generated turbulence in a sheared, stratified natural flow, as well as an analysis of the external factors leading to its generation and temporal variability.
Orton, P. M., Visbeck, Martin
core   +1 more source

Assessing Karenia brevis red tide as a mortality factor of sea turtles in Florida, USA.

Diseases of Aquatic Organisms, 2019
Data on Karenia brevis red tides (≥105 cells l-1) and on dead or debilitated (i.e. stranded) Kemp's ridleys Lepidochelys kempii, loggerheads Caretta caretta, green turtles Chelonia mydas, hawksbills Eretmochelys imbricata, and leatherbacks Dermochelys ...
A. Foley, B. Stacy, P. Schueller, L. Flewelling, B. Schroeder, Karrie Minch, D. Fauquier, J. Foote, C. Manire, Karen Atwood, April A. Granholm, J. Landsberg   +11 more
semanticscholar   +1 more source