Results 111 to 120 of about 1,075,897 (355)
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Redox-Switchable Chalcogen Bonding for Anion Recognition and Sensing
, 2022 Inspired by the success of its related sigma-hole congener halogen bonding (XB), chalcogen bonding (ChB) is emerging as a powerful noncovalent interaction with a plethora of applications in supramolecular chemistry and beyond.
Robert Hein +7 more
core +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Redox-Tunable Valence Tautomerism in a Cobalt Schiff Base Complex
, 2016 Redox-Tunable Valence Tautomerism in a Cobalt Schiff Base ...
David N. Hendrickson (2176894) +4 more
core +1 more source
Nitrate elimination by denitrification in hardwood forest soils of the Upper Rhine floodplain – correlation with redox potential and organic matter [PDF]
, 2002 Denitrification in floodplains is a major issue for river- and groundwater quality. In the Upper Rhine valley, floodplain forests are about to be restored to serve as flood retention areas (polders).
Trémolières, Michèle +2 more
core +1 more source
Redox-Modulated Recognition of Flavin by Functionalized Gold Nanoparticles
, 2016 Redox-Modulated Recognition of Flavin by Functionalized Gold ...
Vincent M. Rotello (179221) +1 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
On The Hidden Structure of Odd Numbers and Its Consequences for the Riemann Hypothesis
Jambura Journal of MathematicsThe Riemann hypothesis remains unconfirmed or invalidated to this day, although local verifications on the calculation of its zeros have never found it faulty.
Junior Mukomene
doaj +1 more source
Metabolites, 2014 Understanding the spatial distribution of bioactive small molecules is indispensable for elucidating their biological or pharmaceutical roles. Mass spectrometry imaging (MSI) enables determination of the distribution of ionizable molecules present in ...
Yoshinori Fujimura, Daisuke Miura
doaj +1 more source