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Redox signaling

Molecular and Cellular Biochemistry, 2002
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have recently been shown to be involved in a multiplicity of physiological responses through modulation of signaling pathways. Some of the specific signaling components altered by reactive oxygen and nitrogen species (RONS) have begun to be identified.
Henry Jay, Forman   +2 more
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Redox imbalance

Cell and Tissue Research, 2004
Substantial evidence implies that redox imbalance attributable to an overproduction of reactive oxygen species or reactive nitrogen species that overwhelm the protective defense mechanism of cells contributes to all forms of Parkinson's disease. Factors such as dopamine, neuromelanin, and transition metals may, under certain circumstances, contribute ...
Daniela, Berg   +2 more
openaire   +2 more sources

Redox clocks: Time to rethink redox interventions

Free Radical Biology and Medicine, 2018
Redox interventions have been controversial in the management of chronic disease. The key reason is believed to be a lack of clarity in our understanding of how endogenous dynamics unfold in biochemical redox mechanisms in live cells. Time-resolved, quantitative research strategies combined with high throughput analysis tools may result in realistic ...
Andras D, Nagy, Akhilesh B, Reddy
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Redox-capacitor to connect electrochemistry to redox-biology

The Analyst, 2014
It is well-established that redox-reactions are integral to biology for energy harvesting (oxidative phosphorylation), immune defense (oxidative burst) and drug metabolism (phase I reactions), yet there is emerging evidence that redox may play broader roles in biology (e.g., redox signaling).
Eunkyoung, Kim   +5 more
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The redox code of plants

Plant, Cell & Environment, 2023
AbstractCentral metabolism is organised through high‐flux, Nicotinamide Adenine Dinucleotide (NAD+/NADH) and NADP+/NADPH systems operating at near equilibrium. As oxygen is indispensable for aerobic organisms, these systems are also linked to the levels of reactive oxygen species, such as H2O2, and through H2O2 to the regulation of macromolecular ...
Ron Mittler, Dean P. Jones
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Redox Control, Redox Signaling, and Redox Homeostasis in Plant Cells

2003
Redox chemistry is a key feature of life. Oxidized substrates are reduced to synthesize functional molecules; reduced substrates are oxidized for energy supply. In addition, cells must fight against uncontrolled oxidation of essential constituents, a process that continuously occurs in an atmosphere of 21% O2. The redox situation is further complicated
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Redox Control of Apoptosis

Antioxidants & Redox Signaling, 2005
[No abstract available]
openaire   +4 more sources

Novel insights into redox system and the mechanism of redox regulation

Molecular Biology Reports, 2016
In view of the critical role of redox system in numerous physiological and pathophysiological processes, it is important to clearly understand the family members and regulatory mechanism of redox system. In this work, we will systematically review the current data detailing the reactive oxygen species (ROS), enzymatic and non-enzymatic antioxidants and
Xin, Wang, Chunxu, Hai
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Redox State and Redox Environment in Biology

2006
Cells and tissues must maintain a reducing environment to survive. This reducing environment provides the electrochemical gradient needed for electron flow. This movement of electrons provides the energy needed to build and maintain cellular structures and associated functions. An array of redox couples is responsible for the electron transfer. Some of
Freya Q. Schafer, Garry R. Buettner
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Homocysteine and Redox Signaling

Antioxidants & Redox Signaling, 2005
Homocysteine is a thiol-containing amino acid that has gained notoriety because its elevation in the plasma is correlated with complex and multifactorial diseases, including cardiovascular diseases, neurodegenerative diseases, and neural tube defects.
Cheng-Gang, Zou, Ruma, Banerjee
openaire   +2 more sources

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