Results 131 to 140 of about 171,869 (285)

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Polyhedral Oligomeric Silsesquioxane Based Material for Tumor Heterogeneity MR Visualization and Precise Treatment

SusMat, EarlyView.
ABSTRACT Malignant tumors whose mortality rates up to 97% possess high heterogeneity that leads to rapid growth, strong invasive capability, and low drug sensitivity. Quantitative magnetic resonance imaging enables direct visualization of tumors. However, gadolinium‐based contrast agents used in clinical practice have significant drawbacks of short ...
Xiaochuan Geng, Zhiguo Zhuang, Jiahui Zhang, Xinxin Zhao, Haiying Lyu, Zi Fu, Xi Liu, Ting Qian, Zhihui Li, Tongtong Chen, Qing Zhang, Yan Zhou, Yong Lu, Gang Wei   +13 more
wiley   +1 more source

Structure and Regulation of the Murine Reduced Folate Carrier Gene [PDF]

Journal of Biological Chemistry, 2005
Mingjun Liu, Yubin Ge, Diane C. Cabelof, Amro Aboukameel, Ahmad R. Heydari, Ramzi Mohammad, Larry H. Matherly   +6 more
openaire   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Critical appraisal of pralatrexate in the management of difficult-to-treat peripheral T cell lymphoma

Therapeutics and Clinical Risk Management, 2011
M Casanova, A Medina-Pérez, M Moreno-Beltran, M Mata-Vazquez, A RuedaOncohematology Service, Hospital Costa del Sol, Marbella, SpainAbstract: Aggressive T cell lymphomas are a subgroup of lymphomas with a particularly poor prognosis.
Casanova M, Medina-Pérez A, Moreno-Beltran M, Mata-Vazquez M, Rueda A   +4 more
doaj  

Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.

Cancer research, 1995
The role of a membrane-associated folate binding protein (mFBP) in transport of folate analogues was investigated in three epithelial cell lines that were grown in high folate medium and folate-conditioned medium and express different levels of mFBP: human nasopharyngeal KB cells, monkey kidney MA104 cells, and IGROV-I ovarian carcinoma cells.
Westerhof, G R, Rijnboutt, S, Schornagel, J H, Pinedo, H M, Peters, G J, Jansen, G   +5 more
openaire   +5 more sources

Cell membrane‐coated nanoparticles for dermatological diseases

VIEW, EarlyView.
Skin disorders are challenging to treat due to complex barrier functions and limited conventional therapies. Biomimetic cell membrane‐coated nanoparticles (CM‐NPs) offer a superior nanomedicine approach by evading immune detection and enabling precise targeting.
Shuaijun Zou, Baojie Zhang, Yuanjie Zhu
wiley   +1 more source

Neonatal and Child Growth Monitoring: A Renewed Call for Uptake and Application of International Growth Standards

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective The Guidance for International Growth Standards (GIGS) project aims to improve and promote appropriate application of international growth standards across clinical, research and public health settings. Design A guidance document providing historical and conceptual context to support the appropriate application of international ...
Eric O. Ohuma, Bancy Ngatia, Simon Parker, Sara Strout, Linda Vesel   +4 more
wiley   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

Clinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron, Anishaa Balaji, Jitesh Chauhan, Jack Alder, Xinyi Chen, Anna M. F. Wiegman, Aurelie Poli, Joanna Jacków‐Malinowska, Jack Cheeseman, Daniel I. R. Spencer, James McDonnell, James Spicer, Alexandra J. McCraw, Sophia N. Karagiannis   +13 more
wiley   +1 more source

Microneedles for the treatment of migraine and orofacial pain: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Migraine is a common neurological disorder and a primary headache condition. Despite its central origin, migraine pain may be referred to the orofacial region via trigeminal pathways, resulting in phenotypic overlap with other orofacial pain (OFP) conditions.
Baicheng Cao, Qiuyi Chen, Yuhan Liu, Ruozhou Wu, Bin Li, Qing Cai, Lu Liu   +6 more
wiley   +1 more source