Results 91 to 100 of about 679,415 (356)

Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes

Journal of Lipid Research, 1977
Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes. The activity in freshly isolated leukocytes is low compared to rat liver but can be assayed reliably. The patterns of response
N L Young, V W Rodwell
doaj   +1 more source

Androgenetic alopecia: a review [PDF]

, 2017
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma, Fortuna, MARIA CATERINA, Lenzi, Andrea, Lolli, Francesca, Lombardo, Francesco, Pallotti, Francesco, Rossi, Alfredo, Sansone, Andrea   +7 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Can Molybdenum Fertilization Enhance Protein Content and Digestibility of Sorghum Single Cropped and Intercropped with Cowpea?

Grasses
Molybdenum fertilization represents a viable alternative for improving forage quality, potentially complementing or enhancing the effects of nitrogen fertilization.
Nágila Sabrina Guedes da Silva, Alexandre Campelo de Oliveira, Baltazar Cirino Júnior, Rhaiana Oliveira de Aviz, Kedes Paulo Pereira, Domingos Sávio Marques de Menezes Vieira, Claudenilde de Jesus Pinheiro Costa, Jucelane Salvino de Lima, Jamiles Carvalho Gonçalves de Souza Henrique, Evaristo Jorge Oliveira de Souza   +9 more
doaj   +1 more source

Partial purification from rat liver microsomes of three native protein phosphatases with activity towards HMG-CoA reductase.

Journal of Lipid Research, 1984
A procedure for the isolation and partial purification of three hydroxymethylglutaryl coenzyme A reductase phosphatases in their native high molecular weight form from rat liver microsomes is described for the first time.
M Sitges, G Gil, F G Hegardt
doaj   +1 more source

The nitric oxide response in plant-associated endosymbiotic bacteria [PDF]

, 2011
Nitric oxide (NO) is a gaseous signalling molecule which becomes very toxic due to its ability to react with multiple cellular targets in biological systems. Bacterial cells protect against NO through the expression of enzymes that detoxify this molecule
Andrew J. Gates, Baudouin, Bedmar, Besson-Bard, Bobik, Bueno, Bueno, Cristina Sánchez, Cruz-Ramos, Cueto, David J. Richardson, de Bruijn, del Giudice, Delgado, Elvers, Eulogio J. Bedmar, Frey, Gardner, Gardner, Gilles-Gonzalez, Girard, González, Gómez-Hernández, Hauser, Horchani, Hughes, Juan J. Cabrera, Justino, Kaneko, María J. Delgado, Meakin, Meakin, Meilhoc, Meilhoc, Mesa, Mesa, Mesa, Mills, Moreau, Oldroyd, Pessi, Pii, Pittman, Poole, Pullan, Shimoda, Socorro Mesa, Spiro, Spiro, Sánchez, Sánchez, Sánchez, Tominaga, Torres, Tucker, Tucker, Tucker, van Wonderen   +57 more
core   +1 more source

Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma [PDF]

, 2021
Renjie Dou, Jinjun Qian, Wei Wu, Yanxin Zhang, Yuxia Yuan, Mengjie Guo, Rongfang Wei, Yang Shu, Artur Jurczyszyn, Siegfried Janz, Meral Beksaç, Chunyan Gu, Ye Yang   +12 more
openalex   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Cloning, sequencing, and characterization of the hexahydro-1,3,5-trinitro-1,3,5-triazine degradation gene cluster from Rhodococcus rhodochrous [PDF]

, 2002
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a high explosive which presents an environmental hazard as a major land and groundwater contaminant.
Basran, A, Bruce, N C, Dabbs, E R, Nicklin, S, Rosser, S J, Seth-Smith, H M B, Travis, E R   +6 more
core   +2 more sources

Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced Healthcare Materials, EarlyView.
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo, Hiroki Hatakeyama, Sayaka Oguri, Akiko Obata, Toshihiro Kasuga   +4 more
wiley   +1 more source