Results 91 to 100 of about 854,050 (403)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Activation of HMG-CoA reductase by microsomal phosphatase

Journal of Lipid Research, 1983
HMG-CoA reductase activity can be modulated by a reversible phosphorylation-dephosphorylation with the phosphorylated form of the enzyme being inactive and the dephosphorylated form, active. Phosphatases from diverse sources, including cytosol, have been
K R Feingold, M H Wiley, A H Moser, S R Lear, M D Siperstein   +4 more
doaj   +1 more source

Selenite reduction by Shewanella oneidensis MR-1 is mediated by fumarate reductase in periplasm

Scientific Reports, 2014
In situ reduction of selenite to elemental selenium (Se(0)), by microorganisms in sediments and soils is an important process and greatly affects the environmental distribution and the biological effects of selenium.
Dao-Bo Li, Yuan-Yuan Cheng, Chao Wu, Wen‐Wei Li, Na Li, Zong-Chuang Yang, Z. Tong, Hanqing Yu   +7 more
semanticscholar   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Genome-wide analysis of OPR family genes in Vitis vinifera and the role of VvOPR1 in copper, zinc tolerance

Frontiers in Plant Science
12-oxo-phytodienoic acid reductase (OPR) is one of the key enzymes in the octadecanoid pathway, and it controls the last step of jasmonic acid (JA) biosynthesis.
Shuang-Hong You, Yuan-Ping Chen, Wen-Jing Shi, Xue Li, Zheng Wu, Quan-Hong Yao   +5 more
doaj   +1 more source

Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes

Journal of Lipid Research, 1977
Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes. The activity in freshly isolated leukocytes is low compared to rat liver but can be assayed reliably. The patterns of response
N L Young, V W Rodwell
doaj   +1 more source

Export of honeybee prepromelittin in Escherichia coli depends on the membrane potential but does not depend on proteins secA and secY [PDF]

, 1989
Honeybee prepromelittin (70 amino acid residues), the precursor of an eukaryotic secretory protein, and a hybrid protein between prepromelittin and mouse dihydrofolate reductase (257 amino acid residues) were expressed in Escherichia coli and ...
Cobet, Werner W. E., Mollay, Christa, Müller, Günter, Zimmermann, Richard   +3 more
core  

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

Can Molybdenum Fertilization Enhance Protein Content and Digestibility of Sorghum Single Cropped and Intercropped with Cowpea?

Grasses
Molybdenum fertilization represents a viable alternative for improving forage quality, potentially complementing or enhancing the effects of nitrogen fertilization.
Nágila Sabrina Guedes da Silva, Alexandre Campelo de Oliveira, Baltazar Cirino Júnior, Rhaiana Oliveira de Aviz, Kedes Paulo Pereira, Domingos Sávio Marques de Menezes Vieira, Claudenilde de Jesus Pinheiro Costa, Jucelane Salvino de Lima, Jamiles Carvalho Gonçalves de Souza Henrique, Evaristo Jorge Oliveira de Souza   +9 more
doaj   +1 more source

Partial purification from rat liver microsomes of three native protein phosphatases with activity towards HMG-CoA reductase.

Journal of Lipid Research, 1984
A procedure for the isolation and partial purification of three hydroxymethylglutaryl coenzyme A reductase phosphatases in their native high molecular weight form from rat liver microsomes is described for the first time.
M Sitges, G Gil, F G Hegardt
doaj   +1 more source