Results 41 to 50 of about 6,649,027 (310)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

The Hamiltonian index of a graph and its branch-bonds [PDF]

, 2001
Let $G$ be an undirected and loopless finite graph that is not a path. The minimum $m$ such that the iterated line graph $L^m(G)$ is hamiltonian is called the hamiltonian index of $G,$ denoted by $h(G).$ A reduction method to determine the hamiltonian ...
Broersma, Haitze J., Li, X., Li, Xueliang, Liming, X., Xiong, L.   +4 more
core   +1 more source

Quasi-states, quasi-morphisms, and the moment map

, 2012
We prove that symplectic quasi-states and quasi-morphisms on a symplectic manifold descend under symplectic reduction on a superheavy level set of a Hamiltonian torus action. Using a construction due to Abreu and Macarini, in each dimension at least four
Abreu, Abreu, Banyaga, Batyrev, Biran, Borman, Buhovsky, Calegari, Cardin, Cho, Delzant, Eliashberg, Entov, Entov, Entov, Entov, Entov, Entov, Fukaya, Fukaya, Fukaya, Fukaya, Ginzburg, Givental, Kotschick, Le Roux, Matthew Strom Borman, Maydanskiy, McDuff, McDuff, McDuff, McDuff, Monzner, Oh, Ostrover, Ostrover, Polterovich, Schwarz, Seidel, Shelukhin, Usher, Walker, Wilson, Woodward   +43 more
core   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Information Compression, Intelligence, Computing, and Mathematics [PDF]

, 2015
This paper presents evidence for the idea that much of artificial intelligence, human perception and cognition, mainstream computing, and mathematics, may be understood as compression of information via the matching and unification of patterns.
Wolff, J. Gerard
core  

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Long‐Term Temporal Profile of Motor Recovery After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Limited data is available to describe the temporal profile of long‐term recovery over 1 year after the stroke in patients with spontaneous intracerebral hemorrhage (ICH). Methods A registered multicentral cohort was conducted to consecutively include non‐herniated supratentorial ICH patients from November 2013 to January 2023 ...
Yan Zheng, Fu‐Xin Lin, Ling‐Yun Zhuo, Jian‐Cai Chen, Xin Ge, Xiang‐Lin Chen, Xue‐Jiao Wang, Zhi‐Gang Yao, You‐Liang Tong, Bo Xie, Bai‐Hai Guo, Zhao‐Sheng Sun, Zhi‐Hua Tian, Ping Qiu, Xin‐Ru Lin, Qiu He, Shu‐Na Huang, Ke Ma, Fang‐Yu Wang, Huang‐Cheng Shang‐Guan, Wen‐Hua Fang, Deng‐Liang Wang, Ying Fu, Yuan‐Xiang Lin, De‐Zhi Kang   +24 more
wiley   +1 more source

Ramification in the division fields of elliptic curves with potential supersingular reduction

, 2016
Let d≥1 be fixed. Let F be a number field of degree d, and let E/F be an elliptic curve. Let E(F)tors be the torsion subgroup of E(F). In 1996, Merel proved the uniform boundedness conjecture, i.e., there is a constant B(d), which depends on d but not on
Álvaro Lozano‐Robledo
semanticscholar   +1 more source